Division of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
Division of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts.
Am J Prev Med. 2017 Oct;53(4):559-566. doi: 10.1016/j.amepre.2017.05.007. Epub 2017 Jul 28.
Stigma against sexual minorities is well documented, but its long-term consequences for health-related quality of life (HRQL) are unknown. This study examined stigma-related predictors of sexual orientation disparities in HRQL and their contribution to young adult HRQL disparities.
In 2013, participants (N=7,304, aged 18-31 years) reported sexual orientation (completely heterosexual [CH], mostly heterosexual, bisexual, and lesbian/gay). The EQ5D-5L, preference weighted for the U.S. population, was used to assess HRQL (range, -0.109 [worse than dead] to 1 [full health]). In prior waves conducted during adolescence, participants reported past-year bullying victimization (range, 1 [never] to 5 [several times/week]) and subjective social status (SSS) in their school (range, 1 [top] to 10 [bottom]). Analyses conducted in 2016 used longitudinal, multivariable linear and logistic regression to assess the contribution of bullying victimization and SSS in adolescence to sexual orientation disparities in HRQL in young adulthood, controlling for confounders and stratified by gender.
Compared with CHs, both female and male sexual minorities reported more bullying victimization and lower SSS in adolescence and lower HRQL in young adulthood (HRQL score among women: mostly heterosexual, 0.878; bisexual, 0.839; lesbian, 0.848; CH, 0.913; HRQL score among men: mostly heterosexual, 0.877; bisexual, 0.882; gay, 0.890; CH, 0.925; all p-values <0.05). When bullying and SSS were added into multivariable models, orientation group effect estimates were attenuated substantially, suggesting bullying and lower SSS in adolescence partly explained HRQL disparities in young adulthood.
Stigma-related experiences in adolescence may have lasting adverse effects on sexual minority health in adulthood.
针对性少数群体的污名化现象已有大量记载,但这种污名对健康相关生活质量(HRQL)的长期影响尚不清楚。本研究旨在探讨与污名相关的预测因素对性取向与 HRQL 差异的影响,以及这些因素对年轻成年人 HRQL 差异的贡献。
2013 年,参与者(N=7304 人,年龄 18-31 岁)报告了自己的性取向(完全异性恋[CH]、主要异性恋、双性恋和同性恋/女同性恋)。使用 EQ5D-5L(范围为-0.109[比死亡还差]到 1[完全健康])评估 HRQL。在青少年时期进行的先前波次中,参与者报告了过去一年的欺凌受害情况(范围为 1[从未]到 5[每周几次])和他们在学校的主观社会地位(SSS)(范围为 1[最高]到 10[最低])。2016 年进行的分析采用纵向、多变量线性和逻辑回归来评估青少年时期的欺凌受害和 SSS 对年轻成年人中性取向 HRQL 差异的贡献,同时控制了混杂因素,并按性别进行分层。
与 CH 相比,女性和男性性少数群体在青少年时期报告了更多的欺凌受害和较低的 SSS,以及较低的 HRQL(女性 HRQL 评分:主要异性恋者为 0.878;双性恋者为 0.839;同性恋者为 0.848;CH 为 0.913;男性 HRQL 评分:主要异性恋者为 0.877;双性恋者为 0.882;同性恋者为 0.890;CH 为 0.925;所有 p 值均<0.05)。当将欺凌和 SSS 纳入多变量模型时,取向群体效应估计值明显减弱,这表明青少年时期的污名化相关经历和较低的 SSS 部分解释了成年后 HRQL 差异。
青少年时期与污名相关的经历可能对成年后性少数群体的健康产生持久的不利影响。