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Message in a bottle from the tumor microenvironment: tumor-educated DCs instruct B cells to participate in immunosuppression.

作者信息

Mion Francesca, Tonon Silvia, Valeri Viviana, Pucillo Carlo E

机构信息

Department of Medicine, University of Udine, Udine, Italy.

出版信息

Cell Mol Immunol. 2017 Sep;14(9):730-732. doi: 10.1038/cmi.2017.63. Epub 2017 Jul 31.

DOI:10.1038/cmi.2017.63
PMID:28757609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5596249/
Abstract
摘要

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本文引用的文献

1
Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma.树突状细胞诱导的 B 细胞激活通过白细胞介素 10 信号促进肝癌的免疫特权。
Nat Commun. 2016 Nov 17;7:13453. doi: 10.1038/ncomms13453.
2
CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes.CD5 表达通过激活 B 淋巴细胞中的 MAPK/Erk 途径和上调 TRPC1 通道促进 IL-10 的产生。
Cell Mol Immunol. 2018 Feb;15(2):158-170. doi: 10.1038/cmi.2016.42. Epub 2016 Aug 8.
3
B cell regulation of the anti-tumor response and role in carcinogenesis.B 细胞对肿瘤免疫反应的调控作用及其在肿瘤发生中的作用。
J Immunother Cancer. 2016 Jul 19;4:40. doi: 10.1186/s40425-016-0145-x. eCollection 2016.
4
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.产生白细胞介素-35的B细胞促进胰腺肿瘤的发展。
Cancer Discov. 2016 Mar;6(3):247-55. doi: 10.1158/2159-8290.CD-15-0843. Epub 2015 Dec 29.
5
Interleukin 10-expressing B cells inhibit tumor-infiltrating T cell function and correlate with T cell Tim-3 expression in renal cell carcinoma.表达白细胞介素10的B细胞抑制肾细胞癌中肿瘤浸润性T细胞功能并与T细胞Tim-3表达相关。
Tumour Biol. 2016 Jun;37(6):8209-18. doi: 10.1007/s13277-015-4687-1. Epub 2015 Dec 30.
6
RETRACTED: Aberrant frequency of IL-10-producing B cells and its association with Treg and MDSC cells in Non Small Cell Lung Carcinoma patients.撤回:非小细胞肺癌患者中产生白细胞介素-10的B细胞的异常频率及其与调节性T细胞和髓源性抑制细胞的关联
Hum Immunol. 2016 Jan;77(1):84-89. doi: 10.1016/j.humimm.2015.10.015. Epub 2015 Oct 23.
7
Cognate interaction with iNKT cells expands IL-10-producing B regulatory cells.与不变自然杀伤T细胞(iNKT细胞)的同源相互作用可扩增产生白细胞介素-10的B调节细胞。
Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12474-9. doi: 10.1073/pnas.1504790112. Epub 2015 Sep 21.
8
Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth.调节性B细胞优先聚集在肿瘤引流淋巴结中,并促进肿瘤生长。
Sci Rep. 2015 Jul 20;5:12255. doi: 10.1038/srep12255.
9
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.免疫抑制性浆细胞阻碍T细胞依赖性免疫原性化疗。
Nature. 2015 May 7;521(7550):94-8. doi: 10.1038/nature14395. Epub 2015 Apr 29.
10
Regulatory B cells: origin, phenotype, and function.调节性 B 细胞:起源、表型和功能。
Immunity. 2015 Apr 21;42(4):607-12. doi: 10.1016/j.immuni.2015.04.005.