Message in a bottle from the tumor microenvironment: tumor-educated DCs instruct B cells to participate in immunosuppression.
作者信息
Mion Francesca, Tonon Silvia, Valeri Viviana, Pucillo Carlo E
机构信息
Department of Medicine, University of Udine, Udine, Italy.
出版信息
Cell Mol Immunol. 2017 Sep;14(9):730-732. doi: 10.1038/cmi.2017.63. Epub 2017 Jul 31.
Abstract
摘要
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本文引用的文献
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Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma.树突状细胞诱导的 B 细胞激活通过白细胞介素 10 信号促进肝癌的免疫特权。
Nat Commun. 2016 Nov 17;7:13453. doi: 10.1038/ncomms13453.
2
CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes.CD5 表达通过激活 B 淋巴细胞中的 MAPK/Erk 途径和上调 TRPC1 通道促进 IL-10 的产生。
Cell Mol Immunol. 2018 Feb;15(2):158-170. doi: 10.1038/cmi.2016.42. Epub 2016 Aug 8.
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B cell regulation of the anti-tumor response and role in carcinogenesis.B 细胞对肿瘤免疫反应的调控作用及其在肿瘤发生中的作用。
J Immunother Cancer. 2016 Jul 19;4:40. doi: 10.1186/s40425-016-0145-x. eCollection 2016.
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IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.产生白细胞介素-35的B细胞促进胰腺肿瘤的发展。
Cancer Discov. 2016 Mar;6(3):247-55. doi: 10.1158/2159-8290.CD-15-0843. Epub 2015 Dec 29.
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Interleukin 10-expressing B cells inhibit tumor-infiltrating T cell function and correlate with T cell Tim-3 expression in renal cell carcinoma.表达白细胞介素10的B细胞抑制肾细胞癌中肿瘤浸润性T细胞功能并与T细胞Tim-3表达相关。
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