良性前列腺增生与下尿路症状的病理生理学：当前概念
Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts.
作者信息
Lee Cheng-Ling, Kuo Hann-Chorng
机构信息
Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
出版信息
Tzu Chi Med J. 2017 Apr-Jun;29(2):79-83. doi: 10.4103/tcmj.tcmj_20_17.
Abstract
Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been identified, including age, genetics, hormones, growth factors, inflammation, and lifestyle factors. However, as our knowledge continues to evolve, male LUTS are no longer managed entirely in a prostate-centric fashion. In this article, we review current concepts in the epidemiology, etiology, and pathophysiology of BPE/BPH and male LUTS.
摘要
下尿路症状（LUTS）在老年人群中非常普遍，尤其是在男性中。从历史上看，前列腺肿大被认为是大多数男性下尿路症状病例的病因。已经确定了良性前列腺肿大/增生（BPE/BPH）发展的几个风险因素，包括年龄、遗传、激素、生长因子、炎症和生活方式因素。然而，随着我们的认识不断发展，男性下尿路症状不再完全以前列腺为中心进行处理。在本文中，我们综述了BPE/BPH和男性下尿路症状的流行病学、病因学和病理生理学的当前概念。
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