肉毒杆菌毒素对夜间磨牙症临床疗效的评估
The Evaluation of the Clinical Effects of Botulinum Toxin on Nocturnal Bruxism.
作者信息
Asutay Fatih, Atalay Yusuf, Asutay Hilal, Acar Ahmet Hüseyin
机构信息
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Vefa Diş Polikliniği, Afyonkarahisar, Turkey.
出版信息
Pain Res Manag. 2017;2017:6264146. doi: 10.1155/2017/6264146. Epub 2017 Jul 5.
Abstract
OBJECTIVES
Nocturnal bruxism can be managed by botulinum toxin (Botox®) in patients who have not responded to conservative treatment. The aim of this study was to evaluate the efficacy of botulinum toxin A (BTXA) in the treatment of nocturnal bruxism.
MATERIAL AND METHODS
The retrospective study comprised 25 female patients, aged 23-55 years (mean 35.84 ± 8.41 years). All patients received a single injection of BTXA in the right and left masseters. Evaluation was made by Visual Analogue Scale (VAS) values, complaint duration, onset of effect, and duration of effectiveness.
RESULTS
BTXA produced significant improvements in pain scores. Only 2 adverse events (8%) were recorded.
CONCLUSION
BTX-A is effective in the treatment of nocturnal bruxism.
摘要
目的
对于保守治疗无效的患者，肉毒杆菌毒素（保妥适®）可用于治疗夜间磨牙症。本研究旨在评估A型肉毒杆菌毒素（BTXA）治疗夜间磨牙症的疗效。
材料与方法
这项回顾性研究纳入了25名年龄在23至55岁之间（平均35.84±8.41岁）的女性患者。所有患者均在左右咬肌各注射一次BTXA。通过视觉模拟量表（VAS）评分、主诉持续时间、起效时间和疗效持续时间进行评估。
结果
BTXA使疼痛评分有显著改善。仅记录到2例不良事件（8%）。
结论
BTX-A治疗夜间磨牙症有效。
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