Ormerod A D, Baker R, Watt J, White M I
Dermatologica. 1986;173(1):5-8. doi: 10.1159/000249207.
The effects of brompheniramine maleate (12 mg twice daily in sustained release form) and terfenadine (60 mg twice daily) on the symptoms and well-being of 16 adults with urticaria with or without dermographism were assessed by symptom questionnaire. Following an initial 2-week period without therapy, each drug was taken for 2 weeks in a randomised double-blind cross-over study. Both drugs produced significant relief of itch and rash but only brompheniramine produced significant drowsiness. Brompheniramine maleate was more effective than terfenadine in the patients with dermographism.
通过症状问卷评估了马来酸氯苯那敏（缓释剂型，每日两次，每次12毫克）和特非那定（每日两次，每次60毫克）对16名有或无皮肤划痕症的成人荨麻疹患者症状和健康状况的影响。在最初为期2周的无治疗期后，在一项随机双盲交叉研究中，每种药物服用2周。两种药物均能显著缓解瘙痒和皮疹，但只有马来酸氯苯那敏会导致显著的嗜睡。在有皮肤划痕症的患者中，马来酸氯苯那敏比特非那定更有效。
