Zhang Yingyun, Zhang Yufeng, Gao Lian, Deng Li, Hu Xiao, Zhang Kexin, Li Haiyan
Department of Electronic Engineering, Information School, Yunnan University, Kunming, Yunnan 650091, China.
Department of Electronic Engineering, Information School, Yunnan University, Kunming, Yunnan 650091, China.
Med Eng Phys. 2017 Nov;49:46-55. doi: 10.1016/j.medengphy.2017.07.004. Epub 2017 Jul 29.
This study assessed the variation in the frequency locations in the Doppler ultrasound spectra for the maximum blood flow velocities of in vessels with different degrees of bilaterally axisymmetric stenosis. This was done by comparing the relationship between the velocity distributions and corresponding Doppler power spectra. First, a geometric vessel model with axisymmetric stenosis was established. This made it possible to obtain the blood flow velocity distributions for different degrees of stenosis from the solutions of the Navier-Stokes equations. Then, the Doppler spectra were calculated for the entire segment of the vessel that was covered by the sound field. Finally, the maximum frequency locations for the spectra were determined based on the intersections of the maximum values chosen from the calculated blood flow velocity distributions and their corresponding spectra. The computational analysis showed that the maximum frequencies, which corresponded to the maximum blood flow velocities for different degrees of stenosis, were located at different positions along the spectral falling edges. The location for a normal (stenosis free) vessel was in the middle of the falling edge. For vessels with increasing degrees of stenosis, this location shifted approximately linearly downward along the falling edge. For 40% stenosis, the location reached a position at the falling edge of 0.32. Results obtained using the Field II simulation tool demonstrated the validity of the theoretical analysis and calculations, and may help to improve the maximum velocity estimation accuracy for Doppler blood flow spectra in stenosed vessels.
本研究评估了不同程度双侧轴对称狭窄血管中最大血流速度在多普勒超声频谱中的频率位置变化。通过比较速度分布与相应多普勒功率谱之间的关系来完成此项研究。首先,建立了具有轴对称狭窄的几何血管模型。这使得从纳维 - 斯托克斯方程的解中获得不同狭窄程度的血流速度分布成为可能。然后,计算声场覆盖的血管整个段的多普勒频谱。最后,根据从计算出的血流速度分布及其相应频谱中选取的最大值的交点来确定频谱的最大频率位置。计算分析表明,对应于不同狭窄程度最大血流速度的最大频率位于频谱下降沿的不同位置。正常(无狭窄)血管的位置在下降沿的中间。对于狭窄程度增加的血管,该位置沿下降沿大致线性向下移动。对于40%的狭窄,该位置到达下降沿0.32处的位置。使用Field II模拟工具获得的结果证明了理论分析和计算的有效性,并可能有助于提高狭窄血管中多普勒血流频谱的最大速度估计精度。