Dipartimento Energia " Galileo Ferraris", Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Dipartimento di Oculistica, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 7, 15121, Alessandria, Italy.
Sci Rep. 2017 Jul 31;7(1):6856. doi: 10.1038/s41598-017-07357-8.
Progressive loss-of-vision related to any intraocular disorder is known as glaucoma. Secretion of aqueous humor is physiologically important to provide nutrients and oxygen to the avascular anterior segment and ensuring normal visual function, even if, nowadays reducing the secretory rate to lower intraocular pressure is a major strategy in treating glaucomatous patients. Understanding the mechanisms and regulation of aqueous humor formation is very important to develop possible new approaches to lower intraocular pressure,but today there isn't any comprehensive model of the regulation of these component in forming aqueous humor. In this paper Construcal law is used to suggest how the Cl fluxes can determine the water inflow and outflow, and, consequently, how the intraocular pressure is controlled by these fluxes.
与任何眼内疾病相关的进行性视力丧失被称为青光眼。房水的分泌在为无血管的前段提供营养和氧气以及确保正常视觉功能方面具有生理重要性，即使在当今，降低分泌率以降低眼内压也是治疗青光眼患者的主要策略。了解房水形成的机制和调节对于开发降低眼内压的新方法非常重要，但目前还没有关于这些成分在形成房水中的调节的综合模型。在本文中，构造定律被用于提出 Cl 通量如何决定水的流入和流出，以及这些通量如何控制眼内压。
