Lee Hyun-Joo, Jin Hyunju, You Hyang-Suk, Shim Woo-Haing, Kim Jeong-Min, Kim Gun-Wook, Mun Je-Ho, Kim Hoon-Soo, Ko Hyun-Chang, Kim Byung-Soo, Kim Moon-Bum
Department of Dermatology, Pusan National University School of Medicine, Busan, Korea.
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
Ann Dermatol. 2017 Aug;29(4):433-437. doi: 10.5021/ad.2017.29.4.433. Epub 2017 Jun 21.
The incidence and mortality rates associated with cutaneous melanoma (CM) have steadily increased over the last 20 years. Even with successful treatment, melanoma patients usually experience substantial anxiety regarding the development of terrible recurrence. To date, few studies have investigated various ().
To describe various and to evaluate the risk of subsequent malignant skin disease in patients with CM.
We performed a prospective study between August 2002 and August 2015.
Fifty-six patients presented with a total of 68 . Among them, melanocytic nevus was the most common (n=27), followed by seborrheic keratosis (n=9) and CM recurrence (n=7). Approximately 5.6% of the lesions were diagnosed as malignant skin diseases. This was a single-center study, so the prevalence of malignant skin diseases following primary melanoma may not represent that of all patients with CM.
The results of this study can be referred by dermatologists dealing with melanoma especially when CM patients have too excessive or unrealistic anxiety for melanoma recurrence during postoperative surveillance of CM. However, the importance of postoperative surveillance must still be emphasized because of real risk of melanoma recurrence and other malignant skin.
在过去20年中,皮肤黑色素瘤(CM)的发病率和死亡率一直在稳步上升。即使治疗成功,黑色素瘤患者通常仍会对可怕的复发产生极大焦虑。迄今为止,很少有研究调查各种()。
描述各种()并评估CM患者后续发生恶性皮肤病的风险。
我们在2002年8月至2015年8月期间进行了一项前瞻性研究。
56例患者共出现68处()。其中,黑素细胞痣最为常见(n = 27),其次是脂溢性角化病(n = 9)和CM复发(n = 7)。约5.6%的病变被诊断为恶性皮肤病。这是一项单中心研究,因此原发性黑色素瘤后恶性皮肤病的患病率可能不代表所有CM患者的情况。
本研究结果可供处理黑色素瘤的皮肤科医生参考,尤其是当CM患者在CM术后监测期间对黑色素瘤复发有过度或不切实际的焦虑时。然而,由于黑色素瘤复发和其他恶性皮肤的实际风险,术后监测的重要性仍必须强调。