从一名HIV感染患者黏膜组织中分离出的致病性T4基因型：病例报告
Pathogenic T4 Genotype Isolated from Mucosal Tissue of a Patient with HIV Infection: A Case Report.
作者信息
Memari Fatemeh, Niyyati Maryam, Joneidi Zeynab
机构信息
Dept. of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dept. of Medical Biotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Iran J Parasitol. 2017 Jan-Mar;12(1):143-147.
Opportunistic infections due to free-living amoebae such as Granulomatous Amoebic Encephalitis (GAE), cutaneous acanthamoebiasis and disseminated infections could be the causative agent of mortality in people living with HIV/AIDS. In this study, we report the occurrence of the belonging to the T4 genotype isolated from nasal and oral swabs of a 15-yr-old man with HIV infection. HIV was confirmed using ELISA kit and RT-PCR assay. The isolated strain showed pathogenic potential using thermo and osmotolerance assays. This patient might be vulnerable to develop GAE or disseminated infections and depending on the immunologic status of the patient, this could be a health threat. Monitoring of such patients, appropriate diagnostic procedures and improved-HIV related care can alter the outcome of such infections.
由自由生活阿米巴引起的机会性感染，如肉芽肿性阿米巴脑炎（GAE）、皮肤棘阿米巴病和播散性感染，可能是导致艾滋病毒/艾滋病患者死亡的病原体。在本研究中，我们报告了从一名15岁感染艾滋病毒男性的鼻拭子和口拭子中分离出的属于T4基因型的[具体名称未提及]的情况。使用ELISA试剂盒和RT-PCR检测法确认了艾滋病毒感染。通过耐热性和耐渗透压检测，分离出的菌株显示出致病潜力。该患者可能易患GAE或播散性感染，根据患者的免疫状态，这可能对健康构成威胁。对此类患者进行监测、采取适当的诊断程序以及改善与艾滋病毒相关的护理，可改变此类感染的结局。
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