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多发性疣状血管瘤:一例报告及新的治疗见解

Multiple Verrucous Hemangiomas: A Case Report with New Therapeutic Insight.

作者信息

Singh Jasmeet, Sharma Preeti, Tandon Sidharth, Sinha Surabhi

机构信息

Department of Dermatology, Venereology and Leprosy, Post Graduate Institute of Medical Education and Research (PGIMER) and Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Indian Dermatol Online J. 2017 Jul-Aug;8(4):254-256. doi: 10.4103/idoj.IDOJ_313_16.

DOI:10.4103/idoj.IDOJ_313_16
PMID:28761841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5518576/
Abstract

Verrucous hemangioma is an uncommon congenital vascular malformation, which may clinically masquerade angiokeratoma, lymphangioma circumscriptum, or malignant melanoma. Differentiation is essential owing to varied therapeutic and prognostic implications. We present a rare case of multiple verrucous hemangiomas in a teenage girl who presented with multiple warty lesions over the dorsal aspect of the left foot since birth. Magnetic resonance imaging (MRI) scan was suggestive of a vascular malformation, and skin biopsy showed ectatic blood vessels extending from the papillary dermis into the subcutaneous tissue, diagnostic of verrucous hemangioma. A combination of 0.05% halobetasol propionate with 3% salicylic acid ointment was advised. This therapeutic intervention resulted in significant resolution of the warty lesions over a period of 2 months, following which surgical excision was performed. The implication is that we can use a combination of super potent topical steroid with salicylic acid as an adjunct to surgical resection.

摘要

疣状血管瘤是一种罕见的先天性血管畸形,临床上可能伪装成血管角化瘤、局限性淋巴管瘤或恶性黑色素瘤。由于治疗和预后意义不同,鉴别诊断至关重要。我们报告一例罕见的青少年女性多发性疣状血管瘤病例,该患者自出生以来左脚背出现多个疣状病变。磁共振成像(MRI)扫描提示血管畸形,皮肤活检显示扩张的血管从乳头层真皮延伸至皮下组织,诊断为疣状血管瘤。建议使用0.05%丙酸氯倍他索与3%水杨酸软膏联合治疗。这种治疗干预在2个月内使疣状病变显著消退,之后进行了手术切除。这意味着我们可以将超强效外用类固醇与水杨酸联合使用作为手术切除的辅助手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/ba11fe9177d2/IDOJ-8-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/de20e421e2fa/IDOJ-8-254-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/b2793d0d8c7f/IDOJ-8-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/ba11fe9177d2/IDOJ-8-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/de20e421e2fa/IDOJ-8-254-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/b2793d0d8c7f/IDOJ-8-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f11c/5518576/ba11fe9177d2/IDOJ-8-254-g003.jpg

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