• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

卡介苗免疫疗法治疗膀胱癌所致胸腔积液

Pleural Effusion Caused by Bacillus Calmette-Guérin Immunotherapy for Bladder Cancer.

作者信息

Rachakonda Tara, Kendall Brian, Spivak Adam M, Boltax Jonathan

机构信息

Department of Medicine.

Division of Infectious Disease, and.

出版信息

Open Forum Infect Dis. 2017 Jun 17;4(3):ofx126. doi: 10.1093/ofid/ofx126. eCollection 2017 Summer.

DOI:10.1093/ofid/ofx126
PMID:28761898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5534218/
Abstract

Intravesical bacillus Calmette Guérin (BCG) instillation has been used as immunotherapy for early stage bladder cancer for >40 years. Complications from this therapy are rare but may result in a spectrum of infectious sequelae. Here we describe the case of an elderly man who presented with a pleural effusion and subcutaneous nodule several years after treatment with BCG.

摘要

膀胱内灌注卡介苗（BCG）已作为早期膀胱癌的免疫疗法使用了40多年。这种疗法的并发症很少见，但可能导致一系列感染后遗症。在此，我们描述一例老年男性病例，该患者在接受卡介苗治疗数年之后出现胸腔积液和皮下结节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e4a/5534218/300126d3939c/ofx12602.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e4a/5534218/a562af7a21de/ofx12601.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e4a/5534218/300126d3939c/ofx12602.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e4a/5534218/a562af7a21de/ofx12601.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e4a/5534218/300126d3939c/ofx12602.jpg

相似文献

1
Pleural Effusion Caused by Bacillus Calmette-Guérin Immunotherapy for Bladder Cancer.卡介苗免疫疗法治疗膀胱癌所致胸腔积液
Open Forum Infect Dis. 2017 Jun 17;4(3):ofx126. doi: 10.1093/ofid/ofx126. eCollection 2017 Summer.
2
Clinical Spectrum of Complications Induced by Intravesical Immunotherapy of Bacillus Calmette-Guérin for Bladder Cancer.卡介苗膀胱内免疫疗法治疗膀胱癌所致并发症的临床谱
J Oncol. 2019 Mar 10;2019:6230409. doi: 10.1155/2019/6230409. eCollection 2019.
3
Emerging Immunotherapy Options for bacillus Calmette-Guérin Unresponsive Nonmuscle Invasive Bladder Cancer.卡介苗无应答非肌肉浸润性膀胱癌的新兴免疫治疗选择。
J Urol. 2019 Dec;202(6):1111-1119. doi: 10.1097/JU.0000000000000297. Epub 2019 May 1.
4
Intravesical instillation therapy with bacillus Calmette-Guérin for superficial bladder cancer: study of the mechanism of bacillus Calmette-Guérin immunotherapy.卡介苗膀胱内灌注治疗浅表性膀胱癌：卡介苗免疫治疗机制的研究
Int J Urol. 2007 Feb;14(2):140-6. doi: 10.1111/j.1442-2042.2007.01696.x.
5
Intravesical bacillus Calmette-Guérin instillation in non-muscle-invasive bladder cancer: A review.卡介苗膀胱内灌注治疗非肌层浸润性膀胱癌：综述
Int J Urol. 2018 Jan;25(1):18-24. doi: 10.1111/iju.13410. Epub 2017 Jul 25.
6
Prevention of the Recurrence of Superficial Bladder Cancers: Intravesical Instillation of Bacillus Calmette-guerin Versus Bacillus Calmette-guerin Plus Epirubicin.浅表性膀胱癌复发的预防：卡介苗膀胱内灌注与卡介苗加表柔比星膀胱内灌注的比较
Asian Pac J Cancer Prev. 2000;1(3):217-220.
7
Safety and Efficacy of Intravesical Bacillus Calmette-Guérin Immunotherapy in Patients with Non-Muscle-Invasive Bladder Cancer Presenting with Asymptomatic Bacteriuria: A Systematic Review.卡介苗膀胱内免疫疗法治疗无症状菌尿的非肌层浸润性膀胱癌患者的安全性和有效性：一项系统评价
Urol Int. 2017;99(1):1-5. doi: 10.1159/000477673. Epub 2017 Jun 10.
8
Intravesical Therapy for the Treatment of Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis.经尿道治疗非肌肉浸润性膀胱癌：系统评价和荟萃分析。
J Urol. 2017 May;197(5):1189-1199. doi: 10.1016/j.juro.2016.12.090. Epub 2016 Dec 24.
9
Mycobacteremia and granulomatous hepatitis following initial intravesical bacillus Calmette-Guerin instillation for bladder carcinoma.膀胱癌初次膀胱内灌注卡介苗后发生分枝杆菌血症和肉芽肿性肝炎。
Am J Gastroenterol. 1993 Jul;88(7):1112-5.
10
Intravesical Bacillus Calmette-Guérin therapy for murine bladder tumors: initiation of the response by fibronectin-mediated attachment of Bacillus Calmette-Guérin.卡介苗膀胱内灌注治疗小鼠膀胱肿瘤：卡介苗通过纤连蛋白介导的黏附引发反应。
Cancer Res. 1987 Apr 1;47(7):1762-6.

引用本文的文献

1
Spontaneous Resolution of Miliary Pulmonary Nodules Following Intravesical Bacillus Calmette-Guérin (BCG) Therapy: A Case Report and Literature Review.卡介苗（BCG）膀胱灌注治疗后粟粒性肺结节的自发消退：一例报告及文献复习
Cureus. 2025 Jul 17;17(7):e88179. doi: 10.7759/cureus.88179. eCollection 2025 Jul.

本文引用的文献

1
Systemic BCG infection in a patient with pancytopaenia and fever 9 years after intravesical BCG administration for bladder cancer.膀胱癌膀胱内灌注卡介苗9年后，一名全血细胞减少伴发热患者发生全身性卡介苗感染。
BMJ Case Rep. 2016 May 11;2016:bcr2016215599. doi: 10.1136/bcr-2016-215599.
2
Differences between a probable and proven BCG infection following intravesical instillations: 16 years experience in a tertiary care hospital.膀胱内灌注后可能的与确诊的卡介苗感染之间的差异：一家三级护理医院的16年经验
Diagn Microbiol Infect Dis. 2016 Jul;85(3):338-343. doi: 10.1016/j.diagmicrobio.2016.04.006. Epub 2016 Apr 11.
3
Mycobacterium bovid infection of total knee arthroplasty after bacille Calmette-Guérin therapy for bladder cancer.
卡介苗治疗膀胱癌后全膝关节置换术发生牛分枝杆菌感染
Am J Orthop (Belle Mead NJ). 2015 Feb;44(2):E46-8.
4
Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.卡介苗（BCG）膀胱内灌注作为膀胱癌辅助治疗后的感染：单中心系列研究中的发病率、危险因素及结局，并对文献进行综述
Medicine (Baltimore). 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119.
5
Immunological basis in the pathogenesis and treatment of bladder cancer.膀胱癌发病机制及治疗中的免疫学基础。
Expert Rev Clin Immunol. 2015 Feb;11(2):265-79. doi: 10.1586/1744666X.2015.983082. Epub 2014 Nov 13.
6
Mycobacterium bovis infection of total hip arthroplasty after intravesicular bacille Calmette-Guérin therapy.卡介苗膀胱内灌注治疗后全髋关节置换术发生牛分枝杆菌感染
Am J Orthop (Belle Mead NJ). 2011 Nov;40(11):E226-8.
7
BCGiosis as a presenting feature of a child with chronic granulomatous disease.卡介苗病作为慢性肉芽肿病患儿的表现特征。
Braz J Infect Dis. 2011 Jan-Feb;15(1):83-6. doi: 10.1016/s1413-8670(11)70146-5.
8
Tubercular disease caused by Bacillus of Calmette-Guérin as a local adjuvant treatment of relapsing bladder carcinoma.结核分枝杆菌病由卡介苗引起，作为复发性膀胱癌的局部辅助治疗。
Cancer Biother Radiopharm. 2009 Oct;24(5):621-7. doi: 10.1089/cbr.2009.0668.
9
Neutrophil stimulation with Mycobacterium bovis bacillus Calmette-Guerin (BCG) results in the release of functional soluble TRAIL/Apo-2L.用卡介苗（BCG）刺激中性粒细胞会导致功能性可溶性肿瘤坏死因子相关凋亡诱导配体（TRAIL）/Apo-2L的释放。
Blood. 2005 Nov 15;106(10):3474-82. doi: 10.1182/blood-2005-03-1327. Epub 2005 Jul 21.
10
BCG vaccine. WHO position paper.卡介苗。世界卫生组织立场文件。
Wkly Epidemiol Rec. 2004 Jan 23;79(4):27-38.