Palacios-Saucedo Gerardo C, Hernández-Hernández Talyha Itzel, Rivera-Morales Lydia Guadalupe, Briones-Lara Evangelina, Caballero-Trejo Amílcar, Vázquez-Guillén José M, Amador-Patiño Gustavo I, García-Cabello Ricardo, Solórzano-Santos Fortino, Rodríguez-Padillacs Cristina
Unidad Médica de Alta Especialidad, Hospital de Especialidades No. 25, Instituto Mexicano del Seguro Social (IMSS), Monterrey, N.L., México.
Laboratorio de Inmunología y Virología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Monterrey, N.L., México.
Gac Med Mex. 2017 May-Jun;153(3):361-370.
Group B streptococci (Streptococcus agalactiae) cause a number of infections in women during pregnancy and postpartum, such as urinary tract infection, chorioamnionitis and endometritis, consequently may affect the newborn. Group B streptococci is the most common cause of severe infections in newborns in developed countries. Studies on the epidemiology of group B streptococci infections in Latin America are still limited. This information is also unknown in Mexico, but studies carried out in the center of the country have found high rates of vaginal colonization in pregnant women and there are case series and case reports of newborns. Microbiological and molecular epidemiology studies in Mexico have shown that populations of group B streptococci have a clonal distribution and that there are clones with genetic and phenotypic characteristics of high virulence that appear to be responsible for most of perinatal pathology. However, the actual role of group B streptococci in perinatal pathology in Mexico is unknown. Consequently, whether to perform or not the screening for determining the group B streptococci colonization status in pregnant women, and the indication or not for intrapartum antibiotic prophylaxis to prevent neonatal group B streptococci infection in Mexico, are still controversial.
B族链球菌(无乳链球菌)可在孕期及产后引发多种感染,如尿路感染、绒毛膜羊膜炎和子宫内膜炎,进而可能影响新生儿。在发达国家,B族链球菌是新生儿严重感染的最常见病因。拉丁美洲关于B族链球菌感染流行病学的研究仍然有限。墨西哥也缺乏此类信息,但在该国中部开展的研究发现孕妇阴道定植率很高,并且有新生儿的病例系列和病例报告。墨西哥的微生物学和分子流行病学研究表明,B族链球菌群体呈克隆分布,存在具有高毒力遗传和表型特征的克隆,这些克隆似乎是导致大多数围产期病理的原因。然而,B族链球菌在墨西哥围产期病理中的实际作用尚不清楚。因此,在墨西哥,是否进行筛查以确定孕妇B族链球菌定植状态,以及是否进行产时抗生素预防以预防新生儿B族链球菌感染,仍然存在争议。