Université Paris-Est, ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France.
Cofrac, Paris, France.
Food Chem. 2017 Dec 15;237:849-856. doi: 10.1016/j.foodchem.2017.06.043. Epub 2017 Jun 7.
Infants and toddlers are highly vulnerable to exposure to lead due to its higher absorption in small children than in adults. This study describes the optimisation and validation of a very sensitive method for the determination of low levels of lead in foods mostly consumed by infants and toddlers. This method, based on inductively coupled plasma-mass spectrometry with a programmable temperature cyclonic spray chamber, attained a limit of quantification (LOQ) of 0.6 or 0.9µgPbkg for a liquid or a solid sample, that was improved by a factor 5.6-8.3 compared to the previous method (LOQ: 5µgkg). The analytical method was then applied to 291 food samples from the first French total diet study on infants and toddlers. Lead was detected in most samples at relatively low concentrations (range 0.0-16µgkg). The highest lead concentrations were mainly found in processed food products (e.g. products containing chocolate).
婴幼儿对铅暴露非常敏感，因为相较于成年人，婴幼儿对铅的吸收率更高。本研究描述了一种非常灵敏的方法，用于检测婴幼儿主要食用的食物中的低水平铅。该方法基于电感耦合等离子体质谱法，采用可编程温度循环喷雾室，液体或固体样品的定量限（LOQ）分别为 0.6 或 0.9µgPbkg，与之前的方法相比提高了 5.6-8.3 倍（LOQ：5µgkg）。然后，该分析方法应用于 291 种来自法国婴幼儿首次全面膳食研究的食物样品。大多数样品中的铅含量相对较低（范围 0.0-16µgkg）。铅浓度最高的主要是加工食品（例如含巧克力的产品）。
