Lambert Marine, Inthavong Chanthadary, Hommet Frédéric, Leblanc Jean-Charles, Hulin Marion, Guérin Thierry
Université Paris-Est, ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France.
ANSES, Risk Assessment Department, Maisons-Alfort, France.
Food Chem. 2018 Feb 1;240:997-1004. doi: 10.1016/j.foodchem.2017.08.035. Epub 2017 Aug 12.
This study describes an optimisation and validation process using liquid chromatography coupled with tandem mass spectrometry to quantify acrylamide in foods mainly consumed by infants and toddlers. A limit of quantification of 5µg.kg for both solid and liquid samples was achieved, except for unprepared infant cereals (LOQ of 18µg.kg). The method was then applied to 141 food samples from the first French total diet study on infants and toddlers. Acrylamide was detected in most samples at mean LB/UB concentrations ranging from 0.14 to 102µg.kg. The "Follow-on formula" and "Infant formula" products contained the lowest average content (LB/UB of 0.14/2.2µg.kg and 0.60/2.9µg.kg respectively) and the "Sweet and savoury biscuits and bars" (102µg.kg; n=1 represented by a plain dry biscuit) contained the highest.
本研究描述了一种使用液相色谱-串联质谱联用技术对婴幼儿主要食用的食品中的丙烯酰胺进行定量的优化和验证过程。除未加工的婴儿谷物(定量限为18µg/kg)外,固体和液体样品的定量限均达到5µg/kg。然后将该方法应用于法国首次针对婴幼儿的总膳食研究中的141份食品样本。在大多数样本中检测到了丙烯酰胺,平均低/高浓度范围为0.14至102µg/kg。“后续配方奶粉”和“婴儿配方奶粉”产品的平均含量最低(分别为0.14/2.2µg/kg和0.60/2.9µg/kg),而“甜味和咸味饼干及棒状食品”(102µg/kg;n = 1,以普通干饼干为例)的含量最高。