Yang Xiu-Fang, Cao Xiao-Hui, Ma Yang-Min, Qiao Ke
a Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry, Ministry of Education , Shaanxi University of Science and Technology , Xi'an , China.
Nat Prod Res. 2018 Feb;32(3):302-307. doi: 10.1080/14786419.2017.1356834. Epub 2017 Aug 1.
In the present study, a new analogue of pyrrolezanthine (1) was isolated from the roots of Reynoutria ciliinervis (Nakai) Moldenke. Its structure was elucidated mainly by NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antimicrobial activity of compound 1 was measured, it exhibited potent antifungal activity against Sclerotinia sclerotiorum with MIC value of 31.2 μg/mL.
在本研究中，从虎杖（Reynoutria ciliinervis (Nakai) Moldenke）的根中分离出一种新的吡咯并嘌呤类似物（1）。其结构主要通过核磁共振（NMR）、高分辨电喷雾电离质谱（HR-ESI-MS）和单晶X射线衍射光谱数据来阐明。同时，测定了化合物1的抗菌活性，它对核盘菌表现出强效抗真菌活性，最低抑菌浓度（MIC）值为31.2μg/mL。
