a Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science and Technology , Xi'an Shaanxi 710021 , China.
Nat Prod Res. 2019 Oct;33(19):2777-2783. doi: 10.1080/14786419.2018.1501687. Epub 2018 Nov 6.
A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid () was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound was tested, it exhibited potent antifungal activity against with MIC value of 16 µg/mL and medium antibacterial activity against with MIC value of 32 µg/mL.
一种新的呋喃衍生物，命名为 3-(5-氧代-2,5-二氢呋喃-3-基)丙酸（），首次被分离出来。它的结构通过紫外、红外、核磁共振、高分辨电喷雾质谱和单晶 X 射线衍射光谱数据得到了阐明。同时，对化合物的抗真菌和抗菌活性进行了测试，结果表明其对具有 MIC 值为 16 μg/mL 的较强抗真菌活性，对具有 MIC 值为 32 μg/mL 的中等抗菌活性。
