系好安全带：膜张力驱动片状伪足网络压缩和黏附沉积。
Buckle up: Membrane tension drives lamellipodial network compression and adhesion deposition.
作者信息
Keren Kinneret, Shemesh Tom
机构信息
Department of Physics, Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa, Israel
Network Biology Research Laboratories, Technion - Israel Institute of Technology, Haifa, Israel.
出版信息
J Cell Biol. 2017 Sep 4;216(9):2619-2621. doi: 10.1083/jcb.201706111. Epub 2017 Aug 1.
Whether to spread on a surface or to crawl, cells must apply traction forces to the underlying substrate via adhesion complexes. In this issue, Pontes et al. (2017. https://doi.org/10.1083/jcb.201611117) shed new light on how the interplay among membrane tension, the lamellipodial actin network, and adhesions coordinate the dynamics of spreading fibroblasts.
无论是在表面铺展还是爬行，细胞都必须通过黏附复合体对下方的基质施加牵引力。在本期中，庞特斯等人（2017年。https://doi.org/10.1083/jcb.201611117）揭示了膜张力、片状伪足肌动蛋白网络和黏附之间的相互作用如何协调成纤维细胞铺展的动力学。
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