Tackenberg Michael C, Johnson Carl H, Page Terry L, Daan Serge
Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee, USA.
Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
J Biol Rhythms. 2017 Aug;32(4):291-294. doi: 10.1177/0748730417716685. Epub 2017 Aug 2.
Among the scientific resources that Colin Pittendrigh passed on to his colleagues after his death in 1996 were two unpublished papers. These manuscripts, developed first in the mid-1960s and continually updated and refined through the late 1970s, centered on the development and experimental exploration of a model of circadian entrainment combining aspects of the well-known parametric (continuous) and nonparametric (discrete) models of entrainment. These texts reveal the experimental work surrounding Pittendrigh's determination of the limits of entrainment and the explanation of the bistability phenomenon. These manuscripts are being made publicly available in their final format (February 1978) as supplementary material to this introduction.
1996年科林·皮特恩德里希去世后，留给他同事们的科学资源中有两篇未发表的论文。这些手稿最初写于20世纪60年代中期，并在70年代末不断更新和完善，其核心是昼夜节律夹带模型的开发和实验探索，该模型结合了著名的参数（连续）和非参数（离散）夹带模型的各个方面。这些文本揭示了围绕皮特恩德里希对夹带极限的确定和双稳态现象解释的实验工作。这些手稿将以最终格式（1978年2月）作为本引言的补充材料公开提供。
