Anand A C, Thakur S K, Singh Wary Am, Dham S K
Reader in Medicine, AFMC, Pune.
Gatroenterologist, CH(SC), Pune.
Med J Armed Forces India. 1994 Jan;50(1):15-18. doi: 10.1016/S0377-1237(17)31030-4. Epub 2017 Jun 27.
To derermine if early ambulation was safe in acute viral hepatitis (AVH), 202 patients of uncomplicated AVH were prospectively randomised into two group. Group A (n=100) received conventional treatment with bed rest while group B (n=102) patients were ambulated as soon as their clinical symptoms abated and progressive clinical and biochemical recovery was noted. While mean recovery time in two groups was not significantlly different (28.8 vs 29.7 days), bed rest period in group B was significantly less (28.8 vs 8.6 days). Natural history of the AVH, clinical and biochemical findings and relapse rate over a follow up period of 14 to 16 months, were no different in the two groups. None of the patients developed chronic hepatitis. Early ambulation is there fore safe in uncomplicated AVH and can lead to enormous saving of manhours and hospital resources.
为了确定早期活动在急性病毒性肝炎(AVH)中是否安全,202例无并发症的AVH患者被前瞻性随机分为两组。A组(n = 100)接受卧床休息的传统治疗,而B组(n = 102)患者在临床症状减轻且有临床和生化指标逐渐恢复时即开始活动。虽然两组的平均恢复时间无显著差异(28.8天对29.7天),但B组的卧床休息时间显著缩短(28.8天对8.6天)。在14至16个月的随访期内,两组的AVH自然病程、临床和生化检查结果以及复发率均无差异。两组患者均未发展为慢性肝炎。因此,早期活动在无并发症的AVH中是安全的,并且可以大量节省人力和医院资源。