Kwak Min-Jung, Kwon Soon-Kyeong, Kim Jihyun F
Department of Systems Biology and Division of Life Sciences, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722 Republic of Korea.
Strategic Initiative for Microbiomes in Agriculture and Food, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722 Republic of Korea.
Stand Genomic Sci. 2017 Jul 25;12:44. doi: 10.1186/s40793-017-0257-z. eCollection 2017.
, belonging to the class , was first isolated from sand sediment of a beach in Dokdo, Korea, in 2005. In this study, we determined the genome sequence of FR1436, the type strain of , and analyzed its gene contents. The genome sequence is the second complete one in the genus after that of sp. JS614. It is composed of a 4,376,707-bp chromosome with a G + C content of 72.26%. From the genome sequence, 4,104 CDSs, three rRNA operons, 51 tRNAs, and one tmRNA were predicted, and 71.38% of the genes were assigned putative functions. Through the sequence analysis, dozens of genes involved in steroid metabolism, especially its degradation, were detected. Most of the identified genes were located in large gene clusters, which showed high similarities with the gene clusters in VKM Ac-2033D. Genomic features of associated with steroid catabolism indicate that it could be used for research and application of steroids in science and industry.
于2005年首次从韩国独岛海滩的沙质沉积物中分离出来，属于 类。在本研究中，我们确定了该菌株的模式菌株FR1436的基因组序列，并分析了其基因组成。该基因组序列是该属继 sp. JS614之后的第二个完整基因组序列。它由一条4,376,707 bp的染色体组成，G + C含量为72.26%。从基因组序列中预测出4,104个编码序列、三个rRNA操纵子、51个tRNA和一个tmRNA，并且71.38%的基因被赋予了推定功能。通过序列分析，检测到数十个参与类固醇代谢，尤其是其降解的基因。大多数已鉴定的基因位于大型基因簇中，这些基因簇与 VKM Ac-2033D中的基因簇具有高度相似性。与类固醇分解代谢相关的 的基因组特征表明，它可用于类固醇在科学和工业中的研究与应用。
