Fairbairn Kirsty A, Ceelen Ingrid J M, Skeaff C Murray, Cameron Claire M, Perry Tracy L
1 University of Otago.
2 Invigorate Nutrition.
Int J Sport Nutr Exerc Metab. 2018 Jan 1;28(1):1-9. doi: 10.1123/ijsnem.2017-0157. Epub 2018 Jan 17.
Vitamin D insufficiency is common in athletes and may lower physical performance. Many cross-sectional studies associate vitamin D status with physical performance in athletes; however, there have been few prospective randomized controlled trials with adequate statistical power to test this relationship, and none in the southern hemisphere. Thus, a prospective double-blind, randomized, placebo-controlled intervention trial was conducted involving 57 professional rugby union players in New Zealand. Participants were randomized to receive 50,000 IU of cholecalciferol (equivalent to 3,570 IU/day) or placebo once every two weeks over 11-12 weeks. Serum 25(OH)D concentrations and physical performance were measured at baseline, weeks 5-6, and weeks 11-12. Mean (SD) serum 25(OH)D concentrations for all participants at baseline was 94 (18) nmol/L, with all players above 50 nmol/L. Vitamin D supplementation significantly increased serum 25(OH)D concentrations compared to placebo, with a 32 nmol/L difference between groups at 11-12 weeks (95% CI, 26-38; p < 0.001). Performance in five of the six tests at study completion, including the primary outcome variable of 30-m sprint time, did not differ between the vitamin D supplemented and placebo groups (p > 0.05). Performance on the weighted reverse-grip chin up was significantly higher in players receiving vitamin D compared with placebo, by 5.5 kg (95% CI, 2.0-8.9; p = 0.002). Despite significantly improving vitamin D status in these professional rugby union players, vitamin D supplementation had little impact on physical performance outcomes. Thus, it is unlikely that vitamin D supplementation is an ergogenic aid in this group of athletes.
维生素D不足在运动员中很常见,可能会降低运动表现。许多横断面研究将运动员的维生素D状况与运动表现联系起来;然而,很少有具有足够统计效力的前瞻性随机对照试验来检验这种关系,南半球则没有此类试验。因此,在新西兰对57名职业橄榄球联盟球员进行了一项前瞻性双盲、随机、安慰剂对照干预试验。参与者被随机分组,在11至12周内每两周接受一次50000国际单位的胆钙化醇(相当于每天3570国际单位)或安慰剂。在基线、第5至6周以及第11至12周测量血清25(OH)D浓度和运动表现。所有参与者在基线时的平均(标准差)血清25(OH)D浓度为94(18)nmol/L,所有球员均高于50 nmol/L。与安慰剂相比,补充维生素D显著提高了血清25(OH)D浓度,在第11至12周时两组之间的差异为32 nmol/L(95%可信区间,26 - 38;p < 0.001)。在研究结束时六项测试中的五项测试中,包括30米短跑时间这一主要结果变量,补充维生素D组和安慰剂组之间没有差异(p > 0.05)。接受维生素D的球员在加权反握引体向上测试中的表现显著高于安慰剂组,高出5.5千克(95%可信区间,2.0 - 8.9;p = 0.002)。尽管补充维生素D显著改善了这些职业橄榄球联盟球员的维生素D状况,但对运动表现结果影响不大。因此,补充维生素D不太可能是这群运动员的一种提高运动能力的辅助手段。