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爱泼斯坦-巴尔病毒脱落的第二个部位:子宫颈。

A second site for Epstein-Barr virus shedding: the uterine cervix.

作者信息

Sixbey J W, Lemon S M, Pagano J S

出版信息

Lancet. 1986 Nov 15;2(8516):1122-4. doi: 10.1016/s0140-6736(86)90531-3.

DOI:10.1016/s0140-6736(86)90531-3
PMID:2877273
Abstract

Epstein-Barr virus (EBV) infection of the human uterine cervix was detected in 5 out of 28 women by means of culture and cytohybridization analysis of cervical secretions. Cervical samples from 2 of 14 women contained epithelial cells with EBV DNA, and filtered cervical washings from 4 women contained infectious EBV. The discovery of EBV shedding in its cell-free infectious form from the uterine cervix raises the possibility of venereal transmission, neonatal infection, and EBV involvement in cervical pathology.

摘要

通过对宫颈分泌物进行培养和细胞杂交分析,在28名女性中的5名检测到人类子宫颈的爱泼斯坦-巴尔病毒(EBV)感染。14名女性中有2名的宫颈样本含有EBV DNA的上皮细胞,4名女性的宫颈冲洗液滤液中含有传染性EBV。从子宫颈发现无细胞感染形式的EBV脱落,增加了性传播、新生儿感染以及EBV参与宫颈病理过程的可能性。

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