A Novel MgO-CaO-SiO₂ System for Fabricating Bone Scaffolds with Improved Overall Performance.

Although forsterite (Mg₂SiO₄) possesses good biocompatibility and suitable mechanical properties, the insufficient bioactivity and degradability hinders its further application. In this study, a novel MgO-CaO-SiO₂ system was developed by adding wollastonite (CaSiO₃) into Mg₂SiO₄ to fabricate bone scaffolds via selective laser sintering (SLS). The apatite-forming ability and degradability of the scaffolds were enhanced because the degradation of CaSiO₃ could form silanol groups, which could offer nucleation sites for apatite. Meanwhile, the mechanical properties of the scaffolds grew with increasing CaSiO₃ to 20 wt %. It was explained that the liquid phase of CaSiO₃ promoted the densification during sintering due to its low melting point. With the further increase in CaSiO₃, the mechanical properties decreased due to the formation of the continuous filling phase. Furthermore, the scaffolds possessed a well-interconnected porous structure and exhibited an ability to support cell adhesion and proliferation.