Arabyan Narine, Huang Bihua C, Weimer Bart C
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, California, USA.
100K Pathogen Genome Project, University of California, Davis, California, USA.
Genome Announc. 2017 Aug 3;5(31):e00659-17. doi: 10.1128/genomeA.00659-17.
Chitinases are glycosyl hydrolases that catalyze the hydrolysis of the β-1,4 linkages in complex carbohydrates and those that contain GlcNAc. These enzymes are considered emerging virulence factors during infection because the host glycan changes. This is the release of four single chitinase deletion mutants in serovar Typhimurium LT2.
几丁质酶是糖基水解酶,可催化复杂碳水化合物以及含有N-乙酰葡糖胺的碳水化合物中β-1,4键的水解。这些酶被认为是感染期间新出现的毒力因子,因为宿主聚糖会发生变化。这是鼠伤寒血清型LT2中四个单几丁质酶缺失突变体的释放。