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一名慢性酒精中毒患者中由耐甲氧西林金黄色葡萄球菌（MRSA）引起的非假单胞菌性坏疽性脓皮病。

Non-pseudomonal ecthyma gangrenosum caused by methicillin-resistant S (MRSA) in a chronic alcoholic patient.

作者信息

R G Santhaseelan, Muralidhar Venkiteswaran

机构信息

General Surgery, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.

出版信息

BMJ Case Rep. 2017 Aug 3;2017:bcr-2017-220983. doi: 10.1136/bcr-2017-220983.

DOI:10.1136/bcr-2017-220983
PMID:28775089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5624054/
Abstract

We report for the first time a case of non-pseudomonal ecthyma gangrenosum (EG) caused by methicillin-resistant in a chronic alcoholic without an associated immunocompromised state or disease. EG is an infection of the skin, commonly associated with bacteraemia, though other organisms are also known to be causally related. It usually occurs in patients who are terminally ill and the immunocompromised. In our case, chronic alcoholism with suppression of innate immunity may have led to the development of the condition.

摘要

我们首次报告了一例由耐甲氧西林的[具体细菌名称未给出]引起的非铜绿假单胞菌坏疽性脓皮病（EG），患者为慢性酒精中毒者，无相关免疫功能低下状态或疾病。EG是一种皮肤感染，通常与[具体细菌名称未给出]菌血症相关，不过已知其他微生物也与之有因果关系。它通常发生在晚期患者和免疫功能低下者中。在我们的病例中，慢性酒精中毒伴先天性免疫抑制可能导致了该病症的发生。

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Immune activation and neuroinflammation in alcohol use and HIV infection: evidence for shared mechanisms.酒精使用与HIV感染中的免疫激活和神经炎症：共同机制的证据
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Ecthyma gangrenosum without bacteremia in a previously healthy man: a case report.一名既往健康男性发生无菌血症的坏疽性脓皮病：病例报告
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Chronic alcoholism causes deleterious conditioning of innate immunity.慢性酒精中毒会对先天免疫造成有害影响。
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Nonpseudomonal ecthyma gangrenosum.非假单胞菌性坏疽性脓皮病。
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Pseudomonas septicemia. Illustrated evolution of its skin lesion.假单胞菌败血症。其皮肤病变的演变图示。
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