Gençer Serap, Ozer Serdar, Ege Gül Aylin, Doğan Mustafa, Ak Oznur
Department of Infectious Diseases and Clinical Microbiology, Kartal Dr, Lütfi Kirdar Training and Research Hospital, Istanbul, Turkey.
J Med Case Rep. 2008 Jan 22;2:14. doi: 10.1186/1752-1947-2-14.
Ecthyma gangrenosum is known as a characteristic lesion of Pseudomonas aeruginosa sepsis and is usually seen in immunocompromised patients.
A previously healthy 63-year-old man was admitted with sloughy necrotic ulcerations of the skin over his sternum. He was afebrile and in good condition. A skin biopsy revealed ecthyma gangrenosum. Blood cultures remained sterile, but a culture of biopsy material grew Pseudomonas aeruginosa.
Ecthyma gangrenosum may develop even in the absence of bacteremia and even in immunocompetent patients. It should be considered as a possible diagnosis even when a previously healthy patient has negative blood cultures.
坏疽性脓皮病是铜绿假单胞菌败血症的特征性损害,通常见于免疫功能低下的患者。
一名63岁既往健康的男性因胸骨上方皮肤出现脱屑性坏死溃疡而入院。他无发热,情况良好。皮肤活检显示为坏疽性脓皮病。血培养结果为无菌生长,但活检材料培养出铜绿假单胞菌。
即使在没有菌血症的情况下,甚至在免疫功能正常的患者中也可能发生坏疽性脓皮病。即使既往健康的患者血培养结果为阴性,也应考虑将其作为一种可能的诊断。