CMB Collegium Medicum Berlin, Berlin, Germany.
Department of Dermatology, University of Copenhagen, Roskilde Hospital, Roskilde, Denmark.
J Eur Acad Dermatol Venereol. 2018 Jan;32(1):152-155. doi: 10.1111/jdv.14508. Epub 2017 Aug 29.
Dynamic optical coherence tomography (D-OCT) has recently been introduced in dermatology. In contrast to 'Standard' OCT imaging, which exclusively relies on the morphological analysis of the tissue, D-OCT allows the in vivo visualization of blood flow. Preliminary D-OCT data showed differences in the vascularization of nevus to melanoma transition, suggesting that this technology may help to differentiate between benign and malignant lesions.
Several factors may influence the quality of D-OCT imaging. Therefore, standard operating procedures as well as a common terminology are required for better validation and comparison of the images.
Here, we present practical guidelines for optimal image acquisition and a proposed terminology on vascular patterns observed by D-OCT.
Dynamic OCT allows the morphologic distinction of different vascular shapes (e.g. dots, blobs, curves, lines), their distribution and organization within skin lesions.
D-OCT adds functional information on skin microvasculature and the vascular networks within lesions.
动态光学相干断层扫描（D-OCT）最近已在皮肤科中应用。与仅依赖于组织形态分析的“标准”OCT 成像不同，D-OCT 可在体内可视化血流。初步的 D-OCT 数据显示了痣到黑色素瘤过渡中血管生成的差异，表明该技术可能有助于区分良性和恶性病变。
D-OCT 成像的质量可能受多种因素影响。因此，需要标准操作程序和通用术语，以便更好地验证和比较图像。
本文介绍了最佳图像采集的实用指南和 D-OCT 观察到的血管模式的建议术语。
动态 OCT 可区分不同的血管形状（例如点、团块、曲线、线），以及它们在皮肤病变中的分布和组织。
D-OCT 增加了皮肤微血管和病变内血管网络的功能信息。
