Kukushkin M L, Poluektov M G
Research Institute of General Pathology of Russian Academy of Sciences, Moscow, Russia; Sechenov First Moscow State Medical University, Moscow, Russia.
Sechenov First Moscow State Medical University, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(4. Vyp. 2):19-27. doi: 10.17116/jnevro20171174219-27.
Chronic pain represents the unique pathophysiological condition characterized by the sustainable chemical, morphological and behavioral patterns. Sleep facilitates many chronic pain syndromes by the blockade of nociceptive ways, release of specific neuromediators and the absence of conscious perception in this time. The restriction of sleep duration or disruption of its structure results in intensification of pain while the improvement of sleep leads to the alleviation of pain in some cases.
慢性疼痛代表了一种独特的病理生理状态，其特征为持续的化学、形态学和行为模式。睡眠通过阻断伤害性通路、释放特定神经介质以及此时缺乏意识感知，促进多种慢性疼痛综合征的缓解。睡眠时间的限制或睡眠结构的破坏会导致疼痛加剧，而改善睡眠在某些情况下会减轻疼痛。
