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丹麦前列腺癌患者根治性前列腺切除术后勃起功能及勃起辅助器具使用情况的回顾性研究

A Retrospective Study of Erectile Function and Use of Erectile Aids in Prostate Cancer Patients After Radical Prostatectomy in Denmark.

作者信息

Haahr Martha Kirstine, Azawi Nessn H, Andersen Line Grønbaek, Carlson Steen, Lund Lars

机构信息

Department of Urology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Winsløvparken, Denmark.

Department of Urology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Winsløvparken, Denmark; Department of Urology, Zealand University Hospital, Sygehusvej, Denmark.

出版信息

Sex Med. 2017 Sep;5(3):e156-e162. doi: 10.1016/j.esxm.2017.06.003. Epub 2017 Aug 1.

Abstract

INTRODUCTION

Radical prostatectomy (RP) offers a good long-term cancer control for clinically localized prostate cancer. However, complications such as erectile dysfunction and substantial decreases quality of life of the afflicted men and their sexual partners. Identification of pre-, per-, and postoperative factors that correlate with poor postoperative erectile status must be considered an important step to improving penile rehabilitation.

AIM

To describe postoperative erectile function after RP in a Danish cohort.

METHODS

The medical records of 1,127 patients undergoing RP from March 2003 through September 2014 were reviewed retrospectively with a 12-month follow-up after surgery. In all, 704 patients fulfilling the inclusion criteria were included in the final analysis. Recovery was defined as self-reported erection sufficient for intercourse (ESI) with or without usage of erectile aids.

MAIN OUTCOME MEASURES

Subjective reporting of erectile function and usage erectile aids 12 months after RP.

RESULTS

ESI with or without erectile aids was reported by 226 men (32.1%), among whom 109 (48.2%) required erectile aids. Erectile dysfunction (ED) was reported by 478 men (67.9%) and by 121 (25.3%) despite use of erectile aids. Of men with ED, 155 (22%) stated not being interested in penile rehabilitation, 26 (3.7%) stated not having resumed their sex life 12 months after RP, and 241 (34.2%) had ED and were unsatisfied with the condition. We found that 134 of 445 men (30.1%) who underwent non-nerve-sparing RP had ESI 12 months after RP. Age older than 60.5 years, a high body mass index, comorbidity, and a high American Society of Anesthesiologists score were negative predictors of erectile function 12 months after RP.

CONCLUSION

Twelve months after RP, 32.1% of men had ESI; half these men required the use of erectile aids. Age older than 60.5 years, a high body mass index, comorbidity, and a high American Society of Anesthesiologists score were negative predictors for ED 12 months after RP. Haahr MK, Azawi NH, Andersen LG, et al. A Retrospective Study of Erectile Function and Use of Erectile Aids in Prostate Cancer Patients After Radical Prostatectomy in Denmark. Sex Med 2017;5:e156-e162.

摘要

引言

根治性前列腺切除术(RP)为临床局限性前列腺癌提供了良好的长期癌症控制效果。然而,诸如勃起功能障碍等并发症会显著降低患病男性及其性伴侣的生活质量。识别与术后勃起状态不佳相关的术前、术中及术后因素,必须被视为改善阴茎康复的重要一步。

目的

描述丹麦队列中RP术后的勃起功能。

方法

回顾性分析2003年3月至2014年9月期间接受RP的1127例患者的病历,并在术后进行12个月的随访。最终分析纳入了704例符合纳入标准的患者。恢复定义为自我报告的勃起足以进行性交(ESI),无论是否使用勃起辅助器具。

主要观察指标

RP术后12个月时勃起功能的主观报告及勃起辅助器具的使用情况。

结果

226例男性(32.1%)报告有ESI,无论是否使用勃起辅助器具,其中109例(48.2%)需要使用勃起辅助器具。478例男性(67.9%)报告有勃起功能障碍(ED),其中121例(25.3%)即使使用勃起辅助器具仍有ED。在有ED的男性中,155例(22%)表示对阴茎康复不感兴趣,26例(3.7%)表示RP术后12个月仍未恢复性生活,241例(34.2%)有ED且对病情不满意。我们发现,445例接受非保留神经RP的男性中,134例(30.1%)在RP术后12个月有ESI。年龄大于60.5岁、高体重指数、合并症以及高美国麻醉医师协会评分是RP术后12个月勃起功能的负性预测因素。

结论

RP术后12个月,32.1%的男性有ESI;其中一半男性需要使用勃起辅助器具。年龄大于60.5岁、高体重指数、合并症以及高美国麻醉医师协会评分是RP术后12个月ED的负性预测因素。哈阿尔·MK、阿扎维·NH、安德森·LG等。丹麦前列腺癌患者根治性前列腺切除术后勃起功能及勃起辅助器具使用的回顾性研究。性医学2017;5:e156 - e162。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/002d/5562492/75db006fb77c/gr1.jpg

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