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孔雀鱼(Poecilia latipinna)中促性腺激素细胞的直接调控。II. 神经激素和神经递质。

Direct control of the gonadotroph in a teleost, Poecilia latipinna. II. Neurohormones and neurotransmitters.

作者信息

Groves D J, Batten T F

出版信息

Gen Comp Endocrinol. 1986 May;62(2):315-26. doi: 10.1016/0016-6480(86)90122-x.

DOI:10.1016/0016-6480(86)90122-x
PMID:2877917
Abstract

Pituitaries from male and female mollies were incubated with varying amounts of mammalian LH-RH, arginine vasotocin, dopamine, or serotonin for 18 hr. Ultrastructural differences between control and experimentally treated glands were used to define the direct effects of these neurohormones and neurotransmitters on the gonadotrophic cells of the adenohypophysis. The effects varied in intensity according to the sex and reproductive state of the donor animal. LH-RH stimulated gonadotrophin secretion by the gonadotrophs, as did vasotocin, although to a much lesser extent and with noticeable differences between the sexes. Dopamine inhibited secretion by basally active gonadotrophs and probably from active cells also, although to a lesser extent. Serotonin mildly stimulated secretion at all stages in both sexes. The results of this study indicate the possible involvement of neurohypophysial octapeptides and of monoamines in the direct control of the gonadotroph of Poecilia latipinna.

摘要

将雄性和雌性帆鳉的脑垂体与不同量的哺乳动物促黄体激素释放激素、精氨酸血管加压素、多巴胺或血清素一起孵育18小时。通过对照腺体和经实验处理的腺体之间的超微结构差异来确定这些神经激素和神经递质对腺垂体促性腺细胞的直接作用。这些作用的强度因供体动物的性别和生殖状态而异。促黄体激素释放激素刺激促性腺细胞分泌促性腺激素,血管加压素也有此作用,尽管程度要小得多,且两性之间存在明显差异。多巴胺抑制基础活性促性腺细胞的分泌,可能对活性细胞也有抑制作用,尽管程度较小。血清素在两性的所有阶段都轻微刺激分泌。本研究结果表明,神经垂体八肽和单胺可能参与了对食蚊鱼促性腺细胞的直接控制。

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