Laboratoire de Physiologie des Régulations, UA CNRS 256Campus de Beaulieu, 35042, Rennes Cédex, France.
Fish Physiol Biochem. 1990 May;8(3):199-205. doi: 10.1007/BF00004458.
Aminergic metabolism was studied in discrete brain regions of the postovulated female rainbow trout using a liquid chromatography electrochemical detection method. 3 Methoxytyramine (3MT) was the major dopaminergic catabolite, suggesting that catechol-o-methyl transferase is the main dopamine (DA) catabolic enzyme. Two populations of brain regions were found: one with a high DA content and low 3MT/DA ratio (hypothalamus and telencephalon), suggesting that these regions could present a high density of DA perikarya; the other with a high 3MT/DA ratio (pituitary, preoptic area, myelencephalon and optic tectum) suggesting that these regions could present a high density of DA axonal endings. 5 Hydroxytryptamine (5HT) content differed, but an homogeneous distribution of monoamine oxidase was found in different brain regions. High 5HT content was found in the hypothalamus and telencephalon; 5HT was however not detectable in the pituitary.
采用液相色谱电化学检测法研究了已排卵雌性虹鳟鱼脑区的胺代谢。3-甲氧基酪胺（3MT）是主要的多巴胺分解产物，提示儿茶酚-O-甲基转移酶是多巴胺（DA）的主要分解酶。发现脑区存在两种类型：一种是 DA 含量高、3MT/DA 比值低（下丘脑和端脑），提示这些区域可能有高密度的 DA 胞体；另一种是 3MT/DA 比值高（垂体、视前区、延髓和视顶盖），提示这些区域可能有高密度的 DA 轴突末梢。5-羟色胺（5HT）含量不同，但不同脑区的单胺氧化酶分布均匀。下丘脑和端脑 5HT 含量高；然而，垂体中 5HT 无法检测到。
