在直接口服抗凝剂时代的维生素K拮抗剂：它们还有使用空间吗？ - Suppr

Vitamin K antagonists in the era of direct oral anticoagulants: is there still a room for their use?

作者信息

Dentali Francesco, Galliazzo Silvia, Zuretti Francesca, Gianni Monica

机构信息

Department of Medicine and Surgery, University of Insubria, U.O. Medicina Interna, Ospedale di Circolo, Viale Borri 57, 21100, Varese, Italy.

Department of Cardiology, Tradate Hospital, Tradate, Italy.

出版信息

Intern Emerg Med. 2017 Dec;12(8):1087-1089. doi: 10.1007/s11739-017-1725-6. Epub 2017 Aug 4.

DOI:10.1007/s11739-017-1725-6

PMID:28779447

Abstract

摘要

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Vitamin K antagonists in the era of direct oral anticoagulants: is there still a room for their use?在直接口服抗凝剂时代的维生素K拮抗剂：它们还有使用空间吗？

Intern Emerg Med. 2017 Dec;12(8):1087-1089. doi: 10.1007/s11739-017-1725-6. Epub 2017 Aug 4.

Non-vitamin K oral anticoagulants versus vitamin K antagonists in the treatment of venous thromboembolic disease.非维生素K口服抗凝剂与维生素K拮抗剂治疗静脉血栓栓塞性疾病的比较

Expert Opin Pharmacother. 2016 Oct;17(15):2033-47. doi: 10.1080/14656566.2016.1232393.

[Changes in blood coagulability induced by direct anticoagulants during treatment with anti-vitamin K].抗维生素K治疗期间直接抗凝剂引起的血液凝固性变化

Haematol Lat. 1961 Jul-Sep;4:273-87.

[Vitamin K antagonist, direct oral anticoagulants: Where is the truth?].[维生素K拮抗剂、直接口服抗凝剂：真相究竟何在？]

J Mal Vasc. 2016 Dec;41(6):383-388. doi: 10.1016/j.jmv.2016.10.002. Epub 2016 Nov 3.

POST-NOAC: Portuguese observational study of intracranial hemorrhage on non-vitamin K antagonist oral anticoagulants.非维生素 K 拮抗剂口服抗凝剂相关颅内出血的葡萄牙观察性研究。

Int J Stroke. 2017 Aug;12(6):623-627. doi: 10.1177/1747493016681021. Epub 2016 Dec 1.

Vitamin K and non-vitamin K antagonist oral anticoagulants for non-valvular atrial fibrillation in real-life.维生素K与非维生素K拮抗剂口服抗凝药用于非瓣膜性心房颤动的真实世界研究

Eur J Intern Med. 2016 Sep;33:42-6. doi: 10.1016/j.ejim.2016.06.022. Epub 2016 Jul 6.

Potential antidotes for reversal of old and new oral anticoagulants.用于逆转新旧口服抗凝剂的潜在解毒剂。

Thromb Res. 2014 May;133 Suppl 2:S158-66. doi: 10.1016/S0049-3848(14)50026-6.

Direct oral anticoagulants, vitamin K antagonists, and simple single tooth extraction.直接口服抗凝剂、维生素K拮抗剂与单纯单颗牙拔除术

Clin Oral Investig. 2019 Mar;23(3):1495. doi: 10.1007/s00784-019-02836-w. Epub 2019 Jan 31.

Introduction. Consensus oral anticoagulants: special emphasis on vitamin K antagonists.

J Assoc Physicians India. 2014 Jun;62(6 Suppl):6-9.

[Heparin or anticoagulants (vitamin K antagonists) in the long-term treatment of angina pectoris and for prevention of recurrences of myocardial infarct?].[肝素或抗凝剂（维生素K拮抗剂）用于心绞痛的长期治疗及预防心肌梗死复发？]

Presse Med (1893). 1961 Apr 8;69:767-8.

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Intracranial hemorrhage in anticoagulated patients with mild traumatic brain injury: significant differences between direct oral anticoagulants and vitamin K antagonists.抗凝治疗的轻度创伤性脑损伤患者的颅内出血：直接口服抗凝剂和维生素 K 拮抗剂之间存在显著差异。

Intern Emerg Med. 2018 Oct;13(7):1077-1087. doi: 10.1007/s11739-018-1806-1. Epub 2018 Mar 8.

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Vitamin K antagonist therapy: changes in the treated populations and in management results in Italian anticoagulation clinics compared with those recorded 20 years ago.维生素K拮抗剂治疗：与20年前记录的情况相比，意大利抗凝诊所治疗人群及管理结果的变化。

Intern Emerg Med. 2017 Dec;12(8):1109-1119. doi: 10.1007/s11739-017-1678-9. Epub 2017 May 13.

The association of anticoagulation, ischemic stroke, and hemorrhage in elderly adults with chronic kidney disease and atrial fibrillation.老年慢性肾脏病合并心房颤动患者抗凝、缺血性卒中和出血的相关性。

Kidney Int. 2017 Apr;91(4):928-936. doi: 10.1016/j.kint.2016.10.017. Epub 2016 Dec 22.

Ischaemic and haemorrhagic stroke associated with non-vitamin K antagonist oral anticoagulants and warfarin use in patients with atrial fibrillation: a nationwide cohort study.非维生素 K 拮抗剂口服抗凝剂和华法林在房颤患者中与缺血性和出血性卒中的相关性：一项全国性队列研究。

Eur Heart J. 2017 Mar 21;38(12):907-915. doi: 10.1093/eurheartj/ehw496.

An update on the pharmaceutical management of thrombosis.

Expert Opin Pharmacother. 2016 Nov;17(16):2149-2164. doi: 10.1080/14656566.2016.1241233. Epub 2016 Oct 12.

Outcomes in a Warfarin-Treated Population With Atrial Fibrillation.华法林治疗的心房颤动患者的结局。

JAMA Cardiol. 2016 May 1;1(2):172-80. doi: 10.1001/jamacardio.2016.0199.

Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.非维生素K拮抗剂口服抗凝药与华法林在房颤患者中的疗效和安全性比较：倾向评分加权的全国队列研究

BMJ. 2016 Jun 16;353:i3189. doi: 10.1136/bmj.i3189.

Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report.抗栓治疗 VTE 疾病：CHEST 指南和专家小组报告。

Chest. 2016 Feb;149(2):315-352. doi: 10.1016/j.chest.2015.11.026. Epub 2016 Jan 7.

Safety and effectiveness of oral rivaroxaban versus standard anticoagulation for the treatment of symptomatic deep-vein thrombosis (XALIA): an international, prospective, non-interventional study.口服利伐沙班对比标准抗凝治疗有症状的深静脉血栓形成的安全性和有效性（XALIA）：一项国际前瞻性非干预性研究。

Lancet Haematol. 2016 Jan;3(1):e12-21. doi: 10.1016/S2352-3026(15)00257-4. Epub 2015 Dec 8.

Non-vitamin K oral anticoagulants in patients with pulmonary embolism: a systematic review and meta-analysis of the literature.非维生素K口服抗凝剂用于肺栓塞患者：一项文献系统综述与荟萃分析

Intern Emerg Med. 2015 Jun;10(4):507-14. doi: 10.1007/s11739-015-1249-x. Epub 2015 May 16.

Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.直接口服抗凝剂与维生素 K 拮抗剂治疗急性静脉血栓栓塞症的比较：来自 3 期试验的证据。

Blood. 2014 Sep 18;124(12):1968-75. doi: 10.1182/blood-2014-04-571232. Epub 2014 Jun 24.

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Vitamin K antagonists in the era of direct oral anticoagulants: is there still a room for their use?

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