E305 Scott Laboratory, Department of Mechanical and Aerospace Engineering, The Ohio State University, 201 W 19th Ave, Columbus, OH, 43210-1142, USA.
Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Ann Biomed Eng. 2017 Nov;45(11):2635-2647. doi: 10.1007/s10439-017-1894-5. Epub 2017 Aug 4.
With more than 29,000 OpenSim users, several musculoskeletal models with varying levels of complexity are available to study human gait. However, how different model parameters affect estimated joint and muscle function between models is not fully understood. The purpose of this study is to determine the effects of four OpenSim models (Gait2392, Lower Limb Model 2010, Full-Body OpenSim Model, and Full Body Model 2016) on gait mechanics and estimates of muscle forces and activations. Using OpenSim 3.1 and the same experimental data for all models, six young adults were scaled in each model, gait kinematics were reproduced, and static optimization estimated muscle function. Simulated measures differed between models by up to 6.5° knee range of motion, 0.012 Nm/Nm peak knee flexion moment, 0.49 peak rectus femoris activation, and 462 N peak rectus femoris force. Differences in coordinate system definitions between models altered joint kinematics, influencing joint moments. Muscle parameter and joint moment discrepancies altered muscle activations and forces. Additional model complexity yielded greater error between experimental and simulated measures; therefore, this study suggests Gait2392 is a sufficient model for studying walking in healthy young adults. Future research is needed to determine which model(s) is best for tasks with more complex motion.
有超过 29000 名 OpenSim 用户，有几个具有不同复杂程度的肌肉骨骼模型可用于研究人类步态。然而，不同模型参数如何影响模型之间关节和肌肉功能的估计还不完全清楚。本研究的目的是确定四个 OpenSim 模型（Gait2392、Lower Limb Model 2010、Full-Body OpenSim Model 和 Full Body Model 2016）对步态力学以及肌肉力量和激活估计的影响。使用 OpenSim 3.1 并为所有模型使用相同的实验数据，在每个模型中对六名年轻人进行缩放，再现步态运动学，并进行静态优化以估计肌肉功能。模拟测量值在模型之间的差异最大可达 6.5°膝关节活动范围、0.012 Nm/Nm 峰值膝关节屈曲力矩、0.49 峰值股直肌激活和 462 N 峰值股直肌力。模型之间坐标系定义的差异改变了关节运动学，影响了关节力矩。肌肉参数和关节力矩的差异改变了肌肉激活和力量。更多的模型复杂性导致实验和模拟测量值之间的误差更大；因此，本研究表明 Gait2392 是研究健康年轻成年人行走的足够模型。需要进一步的研究来确定哪个模型（或多个模型）最适合更复杂运动的任务。
