Department of Mechanical and Nuclear Engineering, Khalifa University, Abu Dhabi, UAE.
Department of Biomedical and Biotechnology Engineering, Khalifa University, Abu Dhabi, UAE.
J Neuroeng Rehabil. 2024 Oct 5;21(1):178. doi: 10.1186/s12984-024-01458-y.
Beyond qualitative assessment, gait analysis involves the quantitative evaluation of various parameters such as joint kinematics, spatiotemporal metrics, external forces, and muscle activation patterns and forces. Utilizing multibody dynamics-based musculoskeletal (MSK) modeling provides a time and cost-effective non-invasive tool for the prediction of internal joint and muscle forces. Recent advancements in the development of biofidelic MSK models have facilitated their integration into clinical decision-making processes, including quantitative diagnostics, functional assessment of prosthesis and implants, and devising data-driven gait rehabilitation protocols. Through an extensive search and meta-analysis of over 116 studies, this PRISMA-based systematic review provides a comprehensive overview of different existing multibody MSK modeling platforms, including generic templates, methods for personalization to individual subjects, and the solutions used to address statically indeterminate problems. Additionally, it summarizes post-processing techniques and the practical applications of MSK modeling tools. In the field of biomechanics, MSK modeling provides an indispensable tool for simulating and understanding human movement dynamics. However, limitations which remain elusive include the absence of MSK modeling templates based on female anatomy underscores the need for further advancements in this area.
除了定性评估，步态分析还涉及对各种参数的定量评估，如关节运动学、时空指标、外力以及肌肉激活模式和力量。利用基于多体动力学的肌肉骨骼 (MSK) 建模为预测内部关节和肌肉力量提供了一种省时、经济且非侵入性的工具。最近在开发生物逼真的 MSK 模型方面的进展促进了它们在临床决策过程中的整合，包括定量诊断、假体和植入物的功能评估，以及制定数据驱动的步态康复方案。通过对超过 116 项研究的广泛搜索和荟萃分析，本基于 PRISMA 的系统综述全面概述了不同现有的多体 MSK 建模平台，包括通用模板、针对个体受试者的个性化方法，以及解决静态不定问题所采用的解决方案。此外，它还总结了 MSK 建模工具的后处理技术和实际应用。在生物力学领域，MSK 建模是模拟和理解人体运动动力学的不可或缺的工具。然而，仍然存在一些难以解决的局限性，例如缺乏基于女性解剖结构的 MSK 建模模板，这突显了该领域需要进一步发展。
