Arteaga Marcial Vásquez, Caballero Víctor Murillo, Rengifo Kelman Marín
Nuclear Physics Laboratory and Physics and Mathematics Postgraduate Unit, National University of Trujillo (UNT), Trujillo, Peru.
Nuclear Physics Laboratory and Physics and Mathematics Postgraduate Unit, National University of Trujillo (UNT), Trujillo, Peru.
Appl Radiat Isot. 2018 Aug;138:25-28. doi: 10.1016/j.apradiso.2017.07.054. Epub 2017 Jul 28.
The dose to kidneys of newborns and 1-year old children was calculated using the MIRD methodology. In order to perform renal studies radiopharmaceutical like Tc-DTPA, Tc-MAG3 and Tc-DMSA are used. Here, besides the anatomic and structure information of kidneys another data are provided in benefit of patient, however during the radioisotope decay emitted radiations delivers, totally or partially, their energy. Therefore is important to estimate the internal radiation dose of the organs. The largest dose to kidneys comes from the self-dose and it is due to the charged particles emitted during Tc decay. From the three radiopharmaceutical here used the largest dose to kidneys is due to Tc-DMSA, and the smaller dose is due to Tc-MAG3.
使用医学内照射剂量（MIRD）方法计算了新生儿和1岁儿童肾脏的剂量。为了进行肾脏研究，使用了诸如锝-二乙三胺五乙酸（Tc-DTPA）、锝-巯基乙酰三甘氨酸（Tc-MAG3）和锝-二巯基丁二酸（Tc-DMSA）等放射性药物。在此，除了肾脏的解剖和结构信息外，还为患者提供了其他数据，然而在放射性同位素衰变过程中发射的辐射会全部或部分释放其能量。因此，估计器官的内照射剂量很重要。对肾脏的最大剂量来自自身剂量，这是由于锝衰变过程中发射的带电粒子所致。在所使用的这三种放射性药物中，对肾脏的最大剂量是由Tc-DMSA引起的，而最小剂量是由Tc-MAG3引起的。
