Torović Ljilja, Dimitrov Nina, Assunção Ricardo, Alvito Paula
a University of Novi Sad , Faculty of Medicine, Department of Pharmacy , Novi Sad , Serbia.
b Centre for Hygiene and Human Ecology , Institute of Public Health of Vojvodina , Novi Sad , Serbia.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Nov;34(11):2023-2032. doi: 10.1080/19440049.2017.1364434. Epub 2017 Aug 24.
This study reports for the first time in Serbia the occurrence of patulin in apple-based food and the risk assessment associated with patulin intake by infants and preschool children. In total, 214 samples of infant fruit juices (48), infant purée (66), and juices for children (small package with straw, 100) were collected over 3 years (2013-15) and analysed using HPLC with ultraviolet detection. Patulin was found in 43.8% of infant juices and 16.7% of infant purée, with all values below the legal limit of 10 μg kg (maximum 8.3 and 7.7 μg kg, respectively). The proportion of contaminated samples among fruit juices for children was 43.0%, with the highest patulin concentration at 30.2 μg kg, not exceeding the maximum allowed level of 50 μg kg. Risk assessment of patulin intake by Serbian infants and preschool children, conducted by deterministic and probabilistic approaches, revealed a hazard quotient well below 1, indicating a tolerable exposure level and no health concern.
本研究首次在塞尔维亚报道了苹果类食品中展青霉素的出现情况以及婴儿和学龄前儿童摄入展青霉素的风险评估。在2013年至2015年的3年时间里,共收集了214份婴儿果汁(48份)、婴儿果泥(66份)和儿童果汁(带吸管的小包装,100份)样本,并采用带紫外检测的高效液相色谱法进行分析。在43.8%的婴儿果汁和16.7%的婴儿果泥中发现了展青霉素,所有数值均低于10微克/千克的法定限值(分别最高为8.3和7.7微克/千克)。儿童果汁中受污染样本的比例为43.0%,展青霉素最高浓度为30.2微克/千克,未超过50微克/千克的最大允许水平。通过确定性和概率性方法对塞尔维亚婴儿和学龄前儿童摄入展青霉素的风险评估显示,危害商远低于1,表明暴露水平可耐受,不存在健康问题。