a Infection Prevention and Antimicrobial Stewardship Fellow, Division of Infectious Diseases , Wayne State University/Detroit Medical Center , Detroit , MI , USA.
b Internal Medicine and Infectious Diseases, Infectious Diseases Fellowship Program , Wayne State University , Detroit , MI , USA.
Expert Rev Anti Infect Ther. 2017 Sep;15(9):819-827. doi: 10.1080/14787210.2017.1364992. Epub 2017 Aug 14.
Candida auris is a recently discovered, rapidly emerging fungal pathogen. Infections due to C. auris are hospital-acquired, multidrug resistant and associated with high mortality. Areas covered: This review highlights epidemiology, pathogenesis, microbiological characteristics, clinical presentation, diagnostic challenges and treatment options of C. auris infections. Infection prevention measures to prevent spread of C. auris and special measures during an outbreak situation have also been reviewed. Expert commentary: Rapid emergence of hospital onset C. auris is worrisome. Early diagnosis of C. auris is essential for better outcomes and the implementation of infection prevention measures. Lack of widespread awareness, absence of general availability of diagnostic testing methods, and limited options for treatment of C. auris infections make it a difficult-to-treat pathogen. Further studies are needed for better understanding of this emerging pathogen.
耳念珠菌是一种新近发现的、迅速出现的真菌病原体。耳念珠菌感染是医院获得性的，具有多重耐药性，死亡率高。
本文重点介绍了耳念珠菌感染的流行病学、发病机制、微生物学特征、临床表现、诊断挑战和治疗选择。还回顾了预防耳念珠菌传播的感染防控措施和暴发情况下的特殊措施。
医院获得性耳念珠菌的迅速出现令人担忧。早期诊断耳念珠菌感染对于改善预后和实施感染防控措施至关重要。缺乏广泛的认识、缺乏普遍可用的诊断检测方法以及治疗耳念珠菌感染的选择有限，使得该病原体难以治疗。需要进一步研究以更好地了解这种新出现的病原体。
