Department of Medicine, Division of Infectious Diseases, University of Utah, Salt Lake City, Utah, USA.
Department of Medicine, Division of Infectious Diseases, University of Utah, Salt Lake City, Utah, USA
J Clin Microbiol. 2018 Jan 24;56(2). doi: 10.1128/JCM.01588-17. Print 2018 Feb.
has emerged globally as a multidrug-resistant health care-associated fungal pathogen. Recent reports highlight ongoing challenges due to organism misidentification, high rates of antifungal drug resistance, and significant patient mortality. The predilection for transmission within and between health care facilities possibly promoted by virulence factors that facilitate skin colonization and environmental persistence is unique among species. This minireview details the global emergence of and discusses issues relevant to clinical microbiology laboratories, hospital infection control, and antimicrobial stewardship efforts.
已在全球范围内成为一种具有多重耐药性的与医疗保健相关的真菌病原体。最近的报告强调了由于生物体鉴定错误、抗真菌药物耐药率高以及患者死亡率高而持续存在的挑战。种内和种间在医疗保健机构内传播的倾向可能是由促进皮肤定植和环境持久性的毒力因子所促进的，这在真菌中是独特的。本综述详细介绍了的全球出现情况，并讨论了与临床微生物学实验室、医院感染控制和抗菌药物管理工作相关的问题。
