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以兰伯特-伊顿肌无力综合征为表现的肺腺癌

Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome.

作者信息

Bukhari Sumera, Soomro Rabia, Fawwad Shaikh, Alvarez Chikezie, Wallach Sara

机构信息

St. Francis Medical Center, Seton Hall University, Trenton, NJ, USA.

出版信息

J Investig Med High Impact Case Rep. 2017 Jul 14;5(3):2324709617721251. doi: 10.1177/2324709617721251. eCollection 2017 Jul-Sep.

Abstract

Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs. There are 2 types of LEMS depending on the etiology: paraneoplastic and idiopathic. The paraneoplastic form, which constitutes more than a half of the cases, is mostly associated with intrathoracic neoplasms. Most cases are seen in patients with small cell lung cancer; other subtypes of lung cancer are extremely rare. In this article, we report a case of LEMS as a rare association with adenocarcinoma of the lung.

摘要

兰伯特-伊顿肌无力综合征(LEMS)是一种副肿瘤性神经肌肉接头疾病。LEMS表现为肌肉无力和易疲劳,主要累及下肢近端。根据病因,LEMS有两种类型:副肿瘤性和特发性。副肿瘤性类型占病例的一半以上,大多与胸内肿瘤有关。大多数病例见于小细胞肺癌患者;肺癌的其他亚型极为罕见。在本文中,我们报告一例LEMS与肺腺癌罕见相关的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/458d/5521354/f5f594c7080a/10.1177_2324709617721251-fig1.jpg

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