Mulligan Ryan P, Morash Joel G, DeOrio James K, Parekh Selene G
1 Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
2 Department of Orthopaedic Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
Foot Ankle Int. 2017 Nov;38(11):1222-1228. doi: 10.1177/1071100717722366. Epub 2017 Aug 8.
Liposomal bupivacaine (LB) is widely used in joint arthroplasty, but there is little reported on the use of LB in foot and ankle surgery. Continuous popliteal sciatic nerve block (CPSNB) is more commonly used for major foot and ankle reconstructions. The purpose of this study was to compare use of intraoperative LB injection to CPSNB as a regional anesthetic for total ankle arthroplasty (TAA), with attention to postoperative pain scores, narcotic use, and complications.
Retrospective review of TAA patients of 2 fellowship-trained orthopedic foot and ankle surgeons was performed. Patients received either preoperative single-shot popliteal sciatic nerve block with 0.2% ropivacaine followed by intraoperative injection of LB or preoperative CPSNB alone. Outcomes examined were visual analog scale (VAS) pain score at 8 hours, 24 hours, 1 week, and 3 weeks following surgery; need for opioid pain medication refill; physician office notification for pain issues or other adverse events; and complications within the first 90 days following surgery. Standard statistical analysis was performed, and P < .05 was considered significant. Seventy-five patients were identified who underwent TAA and met inclusion criteria. Forty-one received LB, and 34 received CPSNB.
No statistical difference was seen between groups with regard to complications, emergency department visits, readmissions, reoperations, VAS pain score at any time point, physician office contacts, and narcotic refills. Sixteen of 41 (39%) LB patients had narcotic refills, versus 12 of 34 (35%) CPSNB patients ( P = .81). Two of 41 (5%) LB patients had a complication postoperatively, versus 4 of 34 (12%) CPSNB patients. There were no complications specific to the anesthetic used in either group.
This is the first study evaluating the use of LB for total ankle arthroplasty. Liposomal bupivacaine was safe and effective as an option for regional anesthetic and postoperative pain control, with comparable results to CPSNB.
Level III, retrospective comparative study.
脂质体布比卡因(LB)在关节置换术中广泛应用,但在足踝手术中的应用报道较少。持续腘部坐骨神经阻滞(CPSNB)更常用于足踝部主要重建手术。本研究的目的是比较术中注射LB与CPSNB作为全踝关节置换术(TAA)区域麻醉的效果,重点关注术后疼痛评分、麻醉药物使用及并发症情况。
对2名接受过足踝专科培训的骨科医生治疗的TAA患者进行回顾性研究。患者术前接受0.2%罗哌卡因单次腘部坐骨神经阻滞,随后术中注射LB,或仅接受术前CPSNB。观察的结果包括术后8小时、24小时、1周和3周的视觉模拟量表(VAS)疼痛评分;阿片类镇痛药再次给药的需求;因疼痛问题或其他不良事件的医生办公室通知;以及术后90天内的并发症。进行标准统计学分析,P<0.05被认为具有统计学意义。共确定75例接受TAA且符合纳入标准的患者。41例接受LB,34例接受CPSNB。
两组在并发症、急诊就诊、再入院、再次手术、任何时间点的VAS疼痛评分、医生办公室联系及麻醉药物再次给药方面均无统计学差异。41例LB患者中有16例(39%)需要再次使用麻醉药物,而34例CPSNB患者中有12例(35%)(P = 0.81)。41例LB患者中有2例(5%)术后出现并发症,34例CPSNB患者中有4例(12%)。两组均未出现与所用麻醉相关的特定并发症。
这是第一项评估LB用于全踝关节置换术的研究。脂质体布比卡因作为区域麻醉和术后疼痛控制的一种选择是安全有效的,与CPSNB效果相当。
III级,回顾性比较研究。