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一种负载大量N-(氨丁基)-N-(乙基异鲁米诺)的新型金属有机框架，作为一种高效电化学发光指示剂用于灵敏检测癌细胞上的粘蛋白1。

A novel metal-organic framework loaded with abundant N-(aminobutyl)-N-(ethylisoluminol) as a high-efficiency electrochemiluminescence indicator for sensitive detection of mucin1 on cancer cells.

作者信息

Jiang Xinya, Wang Zili, Wang Haijun, Zhuo Ying, Yuan Ruo, Chai Yaqin

机构信息

Key Laboratory of Luminescence and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

出版信息

Chem Commun (Camb). 2017 Aug 29;53(70):9705-9708. doi: 10.1039/c7cc05495e.

DOI:10.1039/c7cc05495e
PMID:28786441
Abstract

Herein, a high-efficiency electrochemiluminescence (ECL) indicator of an abundant N-(aminobutyl)-N-(ethylisoluminol) functionalized metal-organic framework (ABEI@Fe-MIL-101) was synthesized to construct a biosensor for the ultrasensitive assay of mucin1 on MCF-7 cancer cells with a coreactant HO-free strategy.

摘要

在此，合成了一种高效的电化学发光（ECL）指示剂，即富含N-(氨丁基)-N-(乙基异鲁米诺)功能化的金属有机框架（ABEI@Fe-MIL-101），以构建一种生物传感器，用于采用无共反应剂HO策略对MCF-7癌细胞上的粘蛋白1进行超灵敏检测。

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