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慢性肾衰竭患者的上消化道黏膜——内镜及组织学评估

UPPER GASTROINTESTINAL MUCOSA IN CHRONIC RENAL FAILURE - AN ENDOSCOPIC AND HISTOLOGICAL EVALUATION.

作者信息

Varma P P, Pruthi H S, Thakur S K, Prasher P K, Singh Balwinder, Saini J S

机构信息

Classified Specialist Medicine & Nephrology, Command Hospital (EC), Calcutta 700 027.

Sr Adv (Med & GE), INHS Asvini, Colaba, Mumbai.

出版信息

Med J Armed Forces India. 1999 Oct;55(4):307-309. doi: 10.1016/S0377-1237(17)30355-6. Epub 2017 Jun 26.

Abstract

Over a three year period, 98 patients of moderate to severe chronic renal failure (S creatinine > 5 mg/dl) admitted in our centre were evaluated for upper GI lesions. All patients underwent upper GI endoscopy. In 68% upper GI mucosa was affected. Various lesions encountered were gastritis (25.5%), duodenitis (10.2%), gastroduodenitis (21.4%), telengiectasia (5.1%), and peptic ulcer in 6.1%. In 74 patients three biopsies, one each from antrum, fundus and duodenum were taken. 45.9% of these had chronic gastritis and 14.8% chronic duodenitis. Prevalence of H pylori on histology was 17.56%. 20 patients (9.6%) developed upper GI bleed during hospitalisation. In 17 (85%) patients, where endoscopy could be done, gastritis/duodenitis/oesophagitis were the common underlying lesions.

摘要

在三年时间里,对我院收治的98例中重度慢性肾衰竭(血清肌酐>5mg/dl)患者进行了上消化道病变评估。所有患者均接受了上消化道内镜检查。68%的患者上消化道黏膜受到影响。发现的各种病变包括胃炎(25.5%)、十二指肠炎(10.2%)、胃十二指肠炎(21.4%)、毛细血管扩张(5.1%)以及消化性溃疡(6.1%)。74例患者分别从胃窦、胃底和十二指肠各取了三块活检组织。其中45.9%患有慢性胃炎,14.8%患有慢性十二指肠炎。组织学检查中幽门螺杆菌的感染率为17.56%。20例患者(9.6%)在住院期间发生了上消化道出血。在17例(85%)能够进行内镜检查的患者中,胃炎/十二指肠炎/食管炎是常见的潜在病变。

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本文引用的文献

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