Heatley Nicholas, Harrington Kevin J, Thway Khin
1 Royal Marsden Hospital, London, UK.
2 Institute of Cancer Research, London, UK.
Int J Surg Pathol. 2018 Feb;26(1):31-33. doi: 10.1177/1066896917724889. Epub 2017 Aug 9.
Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. We illustrate a case of MEC of the parotid in a 17-year-old female, in which all these features occurred extensively, such that they accounted for almost the entire neoplasm, and closely mimicked Warthin tumor histologically. This highlights the need for diagnostic awareness of this particular morphologic variant of MEC, as patients could potentially be inappropriately discharged from follow-up if diagnosed with a benign neoplasm.
黏液表皮样癌（MEC）表现出广泛的形态学谱，包括覆盖着突出囊性结构的具有嗜酸性或鳞状化生改变的上皮，以及肿瘤相关淋巴组织。我们举例说明了一名17岁女性腮腺MEC病例，其中所有这些特征广泛存在，以至于它们几乎构成了整个肿瘤，并且在组织学上与沃辛瘤极为相似。这凸显了对MEC这种特殊形态学变异进行诊断识别的必要性，因为如果诊断为良性肿瘤，患者可能会被不适当地终止随访。
