Baeva E A, Selezneva T S, Kucherovskaia T V, Auzinia A V, Glinskaia E V
Zh Mikrobiol Epidemiol Immunobiol. 1986 Oct(10):47-50.
The reactogenic properties of batches of adsorbed DPT vaccine with the normal content of antigens and with the content of diphtheria and tetanus toxoids reduced, respectively, to 10 Lf and 5 BU per immunization dose have been studied under the conditions of a controlled epidemiological trial. The reduced antigenic content of adsorbed DPT vaccine decreased the number of vaccinal reactions 1.8 times, as well as the intensity of their manifestations.
在一项对照流行病学试验的条件下,对吸附百白破疫苗批次的反应原性进行了研究,这些批次疫苗的抗原含量正常,以及白喉和破伤风类毒素含量分别降至每免疫剂量10Lf和5BU。吸附百白破疫苗抗原含量的降低使疫苗反应的数量减少了1.8倍,也降低了其表现的强度。