[抗原剂量降低的百白破疫苗的反应原性]
[Reactogenic properties of a DTP vaccine with a reduced antigen dosage].
作者信息
Baeva E A, Selezneva T S, Kucherovskaia T V, Auzinia A V, Glinskaia E V
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1986 Oct(10):47-50.
PMID:2879401
Abstract
The reactogenic properties of batches of adsorbed DPT vaccine with the normal content of antigens and with the content of diphtheria and tetanus toxoids reduced, respectively, to 10 Lf and 5 BU per immunization dose have been studied under the conditions of a controlled epidemiological trial. The reduced antigenic content of adsorbed DPT vaccine decreased the number of vaccinal reactions 1.8 times, as well as the intensity of their manifestations.
摘要
在一项对照流行病学试验的条件下，对吸附百白破疫苗批次的反应原性进行了研究，这些批次疫苗的抗原含量正常，以及白喉和破伤风类毒素含量分别降至每免疫剂量10Lf和5BU。吸附百白破疫苗抗原含量的降低使疫苗反应的数量减少了1.8倍，也降低了其表现的强度。
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