Baeva E A, Selezneva T S, Rezepov F F, Chebotareva S V, El'nitskaia E A
Zh Mikrobiol Epidemiol Immunobiol. 1986 Oct(10):50-2.
The immunological effectiveness of two batches of adsorbed DPT vaccine, the batch with the normal content of antigens (control) and the batch with the content of diphtheria and tetanus toxoids reduced to 20 Lf/ml and 5 BU/ml respectively (test batch), has been studied under the conditions of controlled trial. As a result, the reduction of the antigenic content of adsorbed DPT vaccine has been found to exert no negative influence on the immunological effectiveness of the diphtheria, tetanus, and pertussis components of this preparation under the conditions of the new immunization schedule.
在对照试验条件下,对两批吸附百白破疫苗的免疫效果进行了研究,一批为抗原含量正常的批次(对照),另一批为白喉和破伤风类毒素含量分别降至20Lf/ml和5BU/ml的批次(试验批次)。结果发现,在新的免疫程序条件下,吸附百白破疫苗抗原含量的降低对该制剂中白喉、破伤风和百日咳成分的免疫效果没有负面影响。