Acute Care Surgery and Trauma Unit, General Surgery Department, Hadassah - Hebrew University Medical Center, Kiriat Hadassah, POB 12000, 91120 Jerusalem, Israel.
Assia Medical Group, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.
World J Emerg Surg. 2017 Aug 7;12:38. doi: 10.1186/s13017-017-0150-5. eCollection 2017.
Acute mesenteric ischemia (AMI) is typically defined as a group of diseases characterized by an interruption of the blood supply to varying portions of the small intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process will eventuate in life threatening intestinal necrosis. The incidence is low, estimated at 0.09-0.2% of all acute surgical admissions. Therefore, although the entity is an uncommon cause of abdominal pain, diligence is always required because if untreated, mortality has consistently been reported in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment and are essential to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques may provide new options. Thus, we believe that a current position paper from World Society of Emergency Surgery (WSES) is warranted, in order to put forth the most recent and practical recommendations for diagnosis and treatment of AMI. This review will address the concepts of AMI with the aim of focusing on specific areas where early diagnosis and management hold the strongest potential for improving outcomes in this disease process. Some of the key points include the prompt use of CT angiography to establish the diagnosis, evaluation of the potential for revascularization to re-establish blood flow to ischemic bowel, resection of necrotic intestine, and use of damage control techniques when appropriate to allow for re-assessment of bowel viability prior to definitive anastomosis and abdominal closure.
急性肠系膜缺血(AMI)通常被定义为一组以小肠不同部位的血液供应中断为特征的疾病,导致缺血和继发性炎症变化。如果不治疗,这一过程将导致危及生命的肠坏死。其发病率较低,估计占所有急性外科入院患者的 0.09-0.2%。因此,尽管 AMI 是腹痛的一种罕见病因,但仍需保持警惕,因为如果不治疗,其死亡率一直报告在 50%左右。早期诊断和及时的外科干预是现代治疗的基石,对于降低与该病症相关的高死亡率至关重要。血管内治疗方法的出现与现代成像技术并行,可能提供新的选择。因此,我们认为有必要发布世界急诊外科学会(WSES)的现行立场文件,提出 AMI 的最新和实用的诊断和治疗建议。本综述将讨论 AMI 的概念,旨在关注早期诊断和治疗在改善该疾病过程中的结果方面具有最大潜力的具体领域。其中一些关键点包括迅速使用 CT 血管造影术来建立诊断,评估重新建立缺血肠血流的血管再通潜力,切除坏死肠,以及在进行确定性吻合和腹部闭合之前,根据需要使用损伤控制技术,重新评估肠活力。