作为病原体的认识方面的最新进展。
Recent advances in understanding as a pathogen.
作者信息
Klockgether Jens, Tümmler Burkhard
机构信息
Molecular Pathology of Cystic Fibrosis Clinical Research Group, Clinic for Paediatric Pneumology, Allergology, and Neonatology, OE 6710, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Centre for Lung Research, Hannover, Germany.
出版信息
F1000Res. 2017 Jul 28;6:1261. doi: 10.12688/f1000research.10506.1. eCollection 2017.
The versatile and ubiquitous is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in infection.
这种多功能且无处不在的[病原体名称未给出]是一种机会致病菌，可在易感人群中引起急性和慢性感染。在此，我们综述了在理解[病原体名称未给出]种群生物学和毒力、其由环二鸟苷酸介导的生活方式转变、它与哺乳动物宿主的相互作用以及III型和VI型分泌系统在[病原体名称未给出]感染中的作用等方面的最新进展。
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