Treggiari Elisabetta, Elliott James W
Willows Veterinary Centre and Referral Service, Highlands Road, Solihull, B90 4NH, West Midlands, UK.
Open Vet J. 2017;7(3):208-213. doi: 10.4314/ovj.v7i3.2. Epub 2017 Jul 19.
A ten-year-old male neutered cross breed dog presented for evaluation of a mass associated with the left scapular bone, identified as a carcinoma. The dog had a malignant pilomatricoma removed from the left lateral thigh 6 months earlier. Histopathology review of the cutaneous and scapular mass identified the same tumour type, confirming metastatic disease; additional metastases to the inguinal lymph node, liver and lungs were identified. Chemotherapy resulted in partial responses/stable disease of very short duration. Bisphosphonates were administered due to lack of a measurable response and worsening of the associated lameness. The patient ultimately developed a symptomatic vertebral metastasis and was euthanased. The dog survived 255 days since medical treatment was started and 455 days since surgical removal of the primary tumour. This case report suggests that medical treatment with the addition of analgesia may be able to palliate clinical signs and possibly extend survival in dogs with metastatic epithelial cancer.
一只10岁已绝育的杂种公犬因左侧肩胛骨处肿物前来评估，经诊断为癌。该犬6个月前在左大腿外侧切除了一个恶性毛母质瘤。对皮肤和肩胛骨肿物的组织病理学检查确定为同一肿瘤类型，证实发生了转移；还发现腹股沟淋巴结、肝脏和肺部有额外转移灶。化疗产生了短期的部分缓解/病情稳定。由于缺乏可测量的反应且相关跛行加重，给予了双膦酸盐治疗。该患者最终出现有症状的椎体转移，随后实施了安乐死。自开始药物治疗以来，这只狗存活了255天，自手术切除原发肿瘤以来存活了455天。本病例报告表明，加用镇痛的药物治疗或许能够缓解犬转移性上皮癌的临床症状，并有可能延长其生存期。
