Kato Hiroki, Ozeki Michio, Fukao Toshiyuki, Matsuo Masayuki
Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Department of Pediatrics, Gifu University School of Medicine, Gifu, Japan.
Jpn J Radiol. 2017 Oct;35(10):606-612. doi: 10.1007/s11604-017-0674-3. Epub 2017 Aug 9.
To assess the MR imaging findings of vertebral involvement in Gorham-Stout disease (GSD), generalized lymphatic anomaly (GLA), and kaposiform lymphangiomatosis (KLA).
Nine patients (three patients with GSD, three with GLA, and three with KLA) who underwent whole-spine MR examinations were included. MR findings of fatty marrow replacement and prolonged T1 and T2 lesions of the vertebrae were retrospectively assessed. Prolonged T1 and T2 lesions were defined as well-defined and round-, oval-, or geographic-shaped areas.
Six patients [one (33%) patient with GSD, two (67%) with GLA, and three (100%) with KLA] showed both fatty marrow replacement and prolonged T1 and T2 lesions. Fatty marrow replacement was seen in the cervical spine of two (33%) patients, thoracic spine of six (100%), lumbar spine of six (100%), and sacral spine of two (33%). Prolonged T1 and T2 lesions were seen in the cervical spine of three (50%) patients, thoracic spine of three (50%), lumbar spine of six (100%), and sacral spine of three (50%).
Both fatty marrow replacement and prolonged T1 and T2 lesions of the vertebrae could be observed in GSD, GLA, and KLA. The most commonly affected site was the lumbar spine, followed by the thoracic spine.
评估戈勒姆-斯托特病（GSD）、泛发性淋巴管异常（GLA）和卡波西样淋巴管瘤病（KLA）中椎体受累的磁共振成像（MR）表现。
纳入9例接受全脊柱MR检查的患者（3例GSD患者、3例GLA患者和3例KLA患者）。回顾性评估椎体脂肪骨髓替代以及T1和T2信号延长病变的MR表现。T1和T2信号延长病变定义为边界清晰的圆形、椭圆形或地图样区域。
6例患者[1例（33%）GSD患者、2例（67%）GLA患者和3例（100%）KLA患者]同时出现脂肪骨髓替代以及T1和T2信号延长病变。2例（33%）患者颈椎出现脂肪骨髓替代，6例（100%）胸椎出现，6例（100%）腰椎出现，2例（33%）骶椎出现。3例（50%）患者颈椎出现T1和T2信号延长病变，3例（50%）胸椎出现，6例（100%）腰椎出现，3例（50%）骶椎出现。
GSD、GLA和KLA中均可观察到椎体脂肪骨髓替代以及T1和T2信号延长病变。最常受累部位是腰椎，其次是胸椎。
