Testal Alicia García, Marín David Hervás, Maset Rafael García, Maicas Pilar Royo, Salvador Inmaculada Soledad Rico, Díaz Pau Olagüe, Najera Jose Enrique Fernández, De Juan Eduardo Torregrosa, Carrera Caterina Benedito
Department of Nephrology, Hospital de Manises, Valencia, Spain.
Unidad de Bioestadística, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Ther Apher Dial. 2017 Oct;21(5):473-477. doi: 10.1111/1744-9987.12545. Epub 2017 Aug 9.
After dialysis ends, urea continued movement causes rebound postdialysis, with values at about 20%. New techniques have been incorporated into hemodialysis, but their relationship with rebound has not yet been studied. This study aimed to quantify urea rebound at 30-min postdialysis during sessions using polysulfone filters and high-flow versus online hemodiafiltration, and to define its correlation with body composition measured by bioimpedance by a cross-sectional study with 69 patients (December 2015 to January 2016). Mean urea rebound was 24.39, which was positively associated with recirculation, Kt/V or hypotension, and showed a negative relationship with online hemodiafiltration. It was not associated with different body composition compartments. To conclude, postdialysis urea rebound remained high with polysulfone dialyzers and low dialysis doses. Online hemodiafiltration could improve postdialysis urea rebound. Different body composition compartments were not related to rebound.
透析结束后，尿素的持续移动会导致透析后反跳，反跳值约为20%。新技术已被应用于血液透析，但它们与反跳的关系尚未得到研究。本研究旨在通过一项对69例患者（2015年12月至2016年1月）的横断面研究，量化使用聚砜膜过滤器和高流量与联机血液透析滤过的透析过程中透析后30分钟时的尿素反跳，并确定其与通过生物电阻抗测量的身体成分的相关性。平均尿素反跳为24.39，与再循环、Kt/V或低血压呈正相关，与联机血液透析滤过呈负相关。它与不同的身体成分部分无关。总之，使用聚砜膜透析器和低透析剂量时，透析后尿素反跳仍然很高。联机血液透析滤过可改善透析后尿素反跳。不同的身体成分部分与反跳无关。
